IMPACT OF COVID-19 ON NEONATAL OUTCOMES: A SYSTEMATIC REVIEW
DOI:
https://doi.org/10.53555/nnas.v9i1.1521Keywords:
COVID-19, Neonatal, Outcomes, Placenta, TransmittedAbstract
The COVID-19 infection is a pandemic that is still continuing strong and is marked by significant morbidity and fatality rates. In order to make effective use of the resources that are available, it is imperative that clinical and biochemical predictors of the severity and mortality associated with COVID-19 infection be identified as quickly as possible. Although it is impossible to be certain, there is a possibility that the SARS-CoV-2 virus can be passed on from mother to child. This transmission, however, has not been confirmed. This relationship discusses the potential interpretation of these results in terms of the effects of SARS-CoV-2 on the placenta and the pathophysiology of pregnant women. It also shows the spectrum of pathological findings from pregnant women with COVID-19 based on the infection status of their infants. Significant variation may be seen in the spectrum of pathological abnormalities between the placentas of pregnant women infected with COVID-19 and those of newborns who were not infected. The severity of maternal sickness or foetal impairment does not entirely explain the high frequency of preterm births and caesarean deliveries as well as the low incidence of breastfeeding that was found in this study. The maternal and perinatal results of COVID-19 infection during pregnancy are not marked by a severe clinical course and are, in fact, rather favorable. At this time, there is no convincing evidence that COVID-19 can be passed from person to person by the vertical route.
References
World Health Organization (WHO). Novel Coronavirus (2019-nCoV): situation report. Geneva; 2020.
Kandula P; Agarwal J. Proteinuria and hypertension with tyrosine kinase inhibitors. Kidney Int. 2011;80(2):1271–7.
Centers for Disease Control and Prevention. 2019 Novel Coronavirus (2019-nCoV). Washington DC; 2020.
Culp WC. Coronavirus disease: in-home isolation room construction. AA Pr. 2020;14.
Liu D, Li L, Wu X, Zheng D, Wang J, Yang L, et al. Pregnancy and Perinatal Outcomes of Women With Coronavirus Disease (COVID-19) Pneumonia: A Preliminary Analysis. AJR Am J Roentgenol. 2020 Jul;215(1):127–32.
Li N, Han L, Peng M, Lv Y, Ouyang Y, Liu K, et al. Maternal and Neonatal Outcomes of Pregnant Women With Coronavirus Disease 2019 (COVID-19) Pneumonia: A Case-Control Study. Clin Infect Dis an Off Publ Infect Dis Soc Am. 2020 Nov;71(16):2035–41.
Khan S, Peng L, Siddique R, Nabi G, Nawsherwan, Xue M, et al. Impact of COVID-19 infection on pregnancy outcomes and the risk of maternal-to-neonatal intrapartum transmission of COVID-19 during natural birth. Infect Control Hosp Epidemiol. 2020 Jun;41(6):748–50.
Cao D, Yin H, Chen J, Tang F, Peng M, Li R, et al. Clinical analysis of ten pregnant women with COVID-19 in Wuhan, China: A retrospective study. Int J Infect Dis IJID Off Publ Int Soc Infect Dis. 2020 Jun;95:294–300.
Ferrazzi E, Frigerio L, Savasi V, Vergani P, Prefumo F, Barresi S, et al. Vaginal delivery in SARS-CoV-2-infected pregnant women in Northern Italy: a retrospective analysis. BJOG. 2020 Aug;127(9):1116–21.
Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet [Internet]. 2020;395(10226):809–15. Available from: https://www.sciencedirect.com/science/article/pii/S0140673620303603
Zhu H, Wang L, Fang C, Peng S, Zhang L, Chang G, et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020 Feb;9(1):51–60.
World Health Organization (WHO). Naming the coronavirus disease (COVID-19) and the virus that causes it. Geneva; 2020.
Webmeter. Coronavirus Age, Sex, Demographics (COVID-19) - Worldometer. www.worldometers.info. 2020.
Wong SF, Chow KM, Leung TN, Ng WF, Ng TK, Shek CC, et al. Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome. Am J Obstet Gynecol. 2004;191(1):292–7.
Zhang J-J, Dong X, Cao Y-Y, Yuan Y-D, Yang Y-B, Yan Y-Q, et al. Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China. Allergy. 2020 Jul;75(7):1730–41.
Cao Y, Cai K, Xiong L. Coronavirus disease 2019: A new severe acute respiratory syndrome from Wuhan in China. Acta Virol. 2020;64(2):245–50.
Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020 Mar;323(11):1061–9.
Schwartz DA, Morotti D. Placental Pathology of COVID-19 with and without Fetal and Neonatal Infection: Trophoblast Necrosis and Chronic Histiocytic Intervillositis as Risk Factors for Transplacental Transmission of SARS-CoV-2. Viruses. 2020;12(11):1308.
Trevisanuto D, Moschino L, Doglioni N, Roehr CC, Gervasi MT, Baraldi E. Neonatal resuscitation where the mother has a suspected or confirmed novel coronavirus (SARS-CoV-2) infection: suggestion for a pragmatic action plan. Neonatology. 2020;117(2):133–40.
Liu J, Li S, Liu J, Liang B, Wang X, Wang H, et al. Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients. EBioMedicine. 2020 May;55:102763.
Chandrasekharan P, Vento M, Trevisanuto D, Partridge E, Underwood MA, Wiedeman J, et al. Neonatal resuscitation and postresuscitation care of infants born to mothers with suspected or confirmed SARS-CoV-2 infection. Am J Perinatol. 2020;37(08):813–24.
Valiathan R, Ashman M, Asthana D. Effects of ageing on the immune system: infants to elderly. Scand J Immunol. 2016;83(4):255–66.
Bunyavanich S, Do A, Vicencio A. Nasal gene expression of angiotensin-converting enzyme 2 in children and adults. Jama. 2020;323(23):2427–9.
Downloads
Published
Issue
Section
License
Copyright (c) 2023 Journal of Advance Research in Applied Science
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Terms & Condition
Submission -
Author can submit the manuscript through our online submission process or email us at the designated email id in contact details.
The other mode of submission not accepted than online and email.
Before submission please read the submission guidelines.
NN Publication accepts only article submitted in pdf/doc/docx/rtf file format. Another format except given file formats will no be considered .
Author will be responsible for the error mistakes in the submission files. The minor changes can be done without any cost after publication. But for major changes NN Publication may charges you the editing charges.
Publication (Online) -
The online publication is scheduled on last date of every month, but it can be delayed by 24 to 48 hours due to editorial process if huge number of articles comes to publish in single issue.
Automatic notificatation email will be sent to the all users on publication of an issue, so its author’s duty to check their email inbox or SPAM folder to get this notification.
After publication of article author can not withdraw their article.
If editor’s found any issue after publication of article then the NN Publication have the authority to remove the article from online website.
No refund will be provided after online publication of article.
Publication (Print) -
The print copy publication are sent as per the author’s request after 2 weeks of online publication of that issue.
NN Publication will ship the article by India Post and provide the consignment number on dispatch of print copy.
NN Publication follows all the guidelines of delivery provided by IndiaPost and hence not responsible for delay in delivery due to any kind of reasons.
Refund of hard copy will not be provided after dispatch or print of the journal.
NN Publication will be responsible for raise a complain if there is any issue occurs in delivery, but still will not be responsible for providing the refund.
NN Publication will be responsible to resend the print copy only and only if the print copy is lost or print copy is damaged in delivery / or there is delay more than 6 months.
According to India Post the delivery should be completed with in 1-3 weeks after dispatch of articles.
Privacy Policy-
NN Publicationl uses the email ids of authors and editors and readers for sending editorial or publication notification only, we do not reveal or sell the email ids to any other website or company.
