https://nnpub.org/index.php/MHS/gateway/plugin/WebFeedGatewayPlugin/atomJournal of Advanced Research in Medical and Health Science (ISSN 2208-2425)2024-03-27T06:44:44+00:00Dr. Karthikeyan Baskareditor.mhs@nnpub.orgOpen Journal Systems<p><em>The <strong>Scopes</strong> of the journal include but are not limited to, the following fields: Clinical Research, Basic Medical Sciences, Public Health and Epidemiology, Medical Education and Training, Healthcare Policy and Management, Healthcare Technology and Innovation, Healthcare Technology and Innovation, Global Health, Mental Health and Psychiatry, Dentistry and Oral Health, Nursing and Allied Health Professions, Pharmaceutical Sciences, Alternative and Complementary Medicine,<strong> </strong>Patient-Centered Care, Medical Imaging, Nutrition and Dietetics, Emergency Medicine, Gerontology and Geriatrics, Environmental Health, Quality Improvement and Patient Safety.</em></p> <h1 style="text-shadow: 0 0 3px #34baeb;">Current Impact Factor : 5.495</h1>https://nnpub.org/index.php/MHS/article/view/2175DIABETES MANAGEMENT IN CHRONIC KIDNEY DISEASE: A COMPREHENSIVE SYSTEMATIC REVIEW2024-03-27T07:57:35+00:00Landong SijabatGuinanti Novettiandari
<p><strong><em>Background:</em></strong><em> </em><em>The increase in type 2 diabetes has positioned it as the leading cause of chronic kidney disease (CKD) and is responsible for approximately half of all cases of end-stage kidney disease (ESKD) worldwide. Managing CKD in diabetic patients entails addressing its complications and minimizing the risk of other associated conditions, such as cardiovascular disease. </em><em>This study aims to serve a comprehensive systematic review on diabetes management in CKD patients in literatures of the last 10 years. </em></p> <p><em><strong>Methods: </strong>The systematic review followed PRISMA 2020 standards and examined full-text English literature published between 2014 and 2024. This review excluded editorials, review papers from the same journal, and submissions without a DOI. Literature was sourced from online platforms such as PubMed, SagePub, SpringerLink, and Google Scholar. </em></p> <p><em><strong>Result: </strong>A total of 43,740 articles were retrieved from online databases (PubMed, SagePub, SpringerLink and Google Scholar). After three rounds of screening, four articles directly relevant to the systematic review were selected for full-text reading and analysis. </em></p> <p><em><strong>Conclusion:</strong> Chronic kidney disease (CKD) is a common and serious complication in individuals with diabetes. Management involves controlling hypertension and hyperglycemia, along with using ACE inhibitors like finerenone and SGLT2 inhibitors such as dapagliflozin, sotagliflozin, and bexagliflozin.</em></p>
2024-03-27T00:00:00+00:00Copyright (c) 2024 Landong Sijabat, Guinanti Novettiandarihttps://nnpub.org/index.php/MHS/article/view/2174PREVALENCE AND MANAGEMENT OF MATERNAL DEATHS DUE TO ECLAMPSIA AND HELLP SYNDROME: A COMPREHENSIVE SYSTEMATIC REVIEW2024-03-27T07:51:51+00:00Mu’arif RamadhanYohanes Putu Arianta
<p><strong><em>Background:</em></strong><em> </em><em>Eclampsia and HELLP syndrome, are serious complications during pregnancy, and pose significant risks to both mother and fetus. Early management of eclampsia and HELLP syndrome before delivery may improve the outcomes for patients. This study aims to systematically review the literature on the prevalence and management of eclampsia and HELLP syndrome regarding maternal deaths in the last 10 years</em><em>. </em></p> <p><em><strong>Methods: </strong>This systematic review used the PRISMA 2020 guidelines and focused on full-text English literature published between 2014 and 2024. Editorials and review papers from the same journal, as well as submissions without a DOI, were not considered. Literature was gathered from online databases such as PubMed, SagePub, and ScienceDirect.</em></p> <p><em> <strong>Result: </strong>In the initial stages, our research team retrieved a total of 9400 articles from reputable sources such as PubMed, SagePub, and Science Direct. After a meticulous three-level screening process, only six articles were deemed directly relevant to our ongoing systematic review and were selected for further analysis through thorough full-text reading. </em></p> <p><em><strong>Conclusion:</strong> </em><em>Eclampsia and HELLP syndrome are both conditions that require treatment. Pregnancy termination and magnesium supplementation prevent eclampsia, while glucocorticoids are crucial for treating HELLP syndrome. Treatment should consider baseline features and long-term implications to address maternal and fetal health and well-being.</em></p>
2024-03-27T00:00:00+00:00Copyright (c) 2024 Mu’arif Ramadhan, Yohanes Putu Ariantahttps://nnpub.org/index.php/MHS/article/view/2173CHARACTERISTICS AND MANAGEMENT OF GONORRHEA : A TEN YEARS SYSTEMATIC REVIEW2024-03-26T12:38:38+00:00Rahmah Ramadhani BaraDary Dzakwan BaraUray Anifa Rahmadita Putri Hendry
<p><strong><em>Background:</em></strong><em> </em><em>Neisseria gonorrhoeae, an obligate human pathogen, is a sexually transmitted disease that causes consequential worldwide morbidity both in resource-abundant and resource-limited nations, and its diagnosis and treatment require costly expenditures annually. Like other sexually transmitted infections (STIs), gonorrhea disproportionately impacts young adult populations.</em><strong><em> </em></strong></p> <p><strong><em>The aim:</em></strong><em> The aim of this study to show about characteristics and management of gonorrhea.<strong> </strong></em></p> <p><em><strong>Methods: </strong>By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Google Scholar were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. </em></p> <p><em><strong>Result: </strong>In the PubMed database, the results of our search get 51 articles, whereas the results of our search on SagePub get 551 articles, on Google Scholar 2410 articles. </em><em>Records remove before screening are 1219, so we get 1793 articles fos screening</em><em>. After we screened based on record exclude, we compiled a total of 12 papers. We included five research that met the criteria. </em></p> <p><em><strong>Conclusion: </strong></em><em>The management of N. gonorrhoeae infections was compromised by a low rate of examining sexual partners, females and testing extragenital specimens, screening for HIV, compliance to follow-up visits, access to nucleic acid amplification tests, and receiving questionable or even obsolete antimicrobial treatment. Therefore, more accurate and comprehensive management of gonorrhea is urgently needed.</em></p>
2024-03-26T00:00:00+00:00Copyright (c) 2024 Rahmah Ramadhani Bara, Dary Dzakwan Bara, Uray Anifa Rahmadita Putri Hendryhttps://nnpub.org/index.php/MHS/article/view/2172ORAL OPIOID ANALGESICS VS SPINAL STEROID INJECTIONS IN THE TREATMENT OF LOW BACK PAIN: A COMPREHENSIVE SYSTEMATIC REVIEW2024-03-26T12:31:42+00:00Wahyu Agus PrastyoArtha Investari NugraheniRirin AzhariBella Merisa LYosie Yulanda PutraAstrid AnandaAfdila Syarfina
<p><strong><em>Introduction: </em></strong><em>Low back pain (LBP) affects a significant portion of the population worldwide, with distinct treatment needs for acute and chronic cases. Despite widespread opioid use, evidence for their efficacy in LBP remains uncertain, highlighting the need for alternative interventions. Minimally invasive procedures like epidural steroid injections offer potential relief for conditions like lumbar disc herniation, but their effectiveness is debated. To address these complexities, we conducted a comprehensive review encompassing various treatment modalities beyond medication, aiming to optimize outcomes and improve quality of life for individuals with LBP. </em></p> <p><em><strong>Method: </strong></em><em>The researchers in this study followed the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines to ensure that their work met the required standards. This was done to ensure the precision and reliability of the conclusions derived from the research.</em><em> </em></p> <p><strong><em>Result: </em></strong><em>Our search produced 13 results. After looking at the titles and summaries, we found 8 papers that fit our criteria. At first, we excluded several articles because they were written in review style and case reports. But after reading the full papers carefully, we included four papers in our final analysis. These papers included retrospective analysis, a randomized, double blind, placebo controlled cross-over study, noninterventional, retrospective 12-week study using anonymized clinical practice data from the German Pain eRegistry, and a retrospective analysis of anonymized, propensity score–matched data. </em></p> <p><em><strong>Conclusion</strong>: Favorable post-injection outcomes suggest the blind method for caudal epidural injections is safe and effective, suitable for patients not eligible for surgery or unresponsive to conservative treatments. Interlaminar epidural steroid injections effectively reduce VAS and ODI scores in patients with chronic low back pain and multi-level disc disease, but further research is needed to standardize administration protocols and optimize treatment outcomes, including addressing BMI's impact. The analgesic efficacy of periradicular meloxicam injections for acute/subacute low back pain, indicating a potential new treatment option, while real-world data suggest NBX oromucosal spray may be superior to typical oral LAO analgesics for severe peripheral NBP, pending confirmation in large RCTs. </em></p>
2024-03-26T00:00:00+00:00Copyright (c) 2024 Wahyu Agus Prastyo, Artha Investari Nugraheni, Ririn Azhari, Bella Merisa L, Yosie Yulanda Putra, Astrid Ananda, Afdila Syarfinahttps://nnpub.org/index.php/MHS/article/view/2171THE EFFECT OF BARIATRIC SURGERY ON BREAST CANCER INCIDENCE AND CHARACTERISTICS: A COMPREHENSIVE SYSTEMATIC REVIEW2024-03-26T12:19:37+00:00Rokhim SuryadiBambang SupriyoYosie Yulanda PutraAhsan AuliyaM. Yudhi Hardiyansah
<p><strong><em>Background:</em></strong><em> </em><em>Obesity elevates estrogen levels and pro-inflammatory cytokines, increasing breast cancer risk via macrophage migration to breast tissue and stimulating epithelial proliferation. Observational studies suggest that intentional weight loss, such as through bariatric surgery, can mitigate this risk. This study aims to conduct a comprehensive systematic review, focusing on the impact of bariatric surgery on breast cancer incidence and characteristics using recent literature.</em><em> </em></p> <p><strong><em>Methods: </em></strong><em>The systematic review followed PRISMA 2020 standards and examined full-text English literature published between 2014 and 2024. This review excluded editorials, review papers from the same journal, and submissions without a DOI. Literature was sourced from online platforms such as PubMed, SagePub, and SpringerLink. </em></p> <p><em><strong>Result: </strong>A total of 1,011 articles s were retrieved from online databases (PubMed, SagePub, and SpringerLink). After three rounds of screening, five articles directly relevant to the systematic review were selected for full-text reading and analysis. </em></p> <p><em><strong>Conclusion:</strong> Bariatric surgery decreases overall cancer risk in women, especially for breast cancer, by lowering estrogen levels and altering tumor biology. It also improves glucose homeostasis and reduces insulin resistance, both linked to higher cancer risk. </em></p>
2024-03-26T00:00:00+00:00Copyright (c) 2024 Rokhim Suryadi, Bambang Supriyo, Yosie Yulanda Putra, Ahsan Auliya, M. Yudhi Hardiyansahhttps://nnpub.org/index.php/MHS/article/view/2170THE EVALUATION AND TREATMENT OF HEMORRHOIDS: AN UPDATED SYSTEMATIC REVIEW2024-03-26T12:11:10+00:00Rokhim SuryadiBambang SupriyoYosie Yulanda PutraAhsan AuliyaM. Yudhi Hardiyansah
<p><strong><em>Background:</em></strong><em> </em><em>Hemorrhoids are naturally occurring veins in the lower rectum and anus that aid in continence. The severity of pain or discomfort associated with hemorrhoids is influenced by factors such as their size, thrombosis, and location relative to the dentate line. During the history-taking and physical examination, it's crucial to identify risk factors and clinical signs that may suggest more serious underlying conditions.</em><em>The objective of this study is to conduct an extensive systematic review involving the evaluation and treatment of hemorrhoids based on literature published within the past decade. </em></p> <p><em><strong>Methods: </strong>The systematic review followed PRISMA 2020 standards and examined full-text English literature published between 2014 and 2024. This review excluded editorials, review papers from the same journal, and submissions without a DOI. Literature was sourced from online platforms such as PubMed, SagePub, and SpringerLink. </em></p> <p><em><strong>R</strong></em><em><strong>esult: </strong>A total of 1,097 articles s were retrieved from online databases (PubMed, SagePub, and SpringerLink). After three rounds of screening, five articles directly relevant to the systematic review were selected for full-text reading and analysis. </em></p> <p><em><strong>Conclusion:</strong> Hemorrhoids require proper diagnosis and management. Pregnancy and inflammation increases the risk of hemorrhoids. Conservative treatments work for mild cases, while surgery may be needed for severe ones. Theres an association between hemorrhoids and colorectal cancer, prompting screening recommendations for patients. </em></p>
2024-03-26T00:00:00+00:00Copyright (c) 2024 Rokhim Suryadi, Bambang Supriyo, Yosie Yulanda Putra, Ahsan Auliya, M. Yudhi Hardiyansahhttps://nnpub.org/index.php/MHS/article/view/2169RISK FACTORS OF PERINATAL DEPRESSION IN WOMEN: AN UPDATED SYSTEMATIC REVIEW2024-03-26T12:02:20+00:00Artha Investari NugraheniDini Amelia RahmahWahyu Agus PrastyoRirin AzhariBella Merisa LAstrid AnandaAfdila Syarfina
<p><strong><em>Background:</em></strong><em> </em><em>Perinatal depression (PND) can result in adverse outcomes for both mother and child, including poorer pregnancy outcomes and long-term emotional, social, and cognitive difficulties in children. Furthermore, it correlates with high morbidity and mortality rates, posing significant burdens on affected individuals, families, and society. </em><em>The objective of this study is to conduct an extensive systematic review evaluating the risk factors of perinatal depression in women based on literature published within the last five years. </em></p> <p><em><strong>Methods: </strong>The systematic review followed PRISMA 2020 standards and examined full-text English literature published between 2019 and 2024. This review excluded editorials, review papers from the same journal, and submissions without a DOI. Literature was sourced from online platforms such as PubMed, SagePub, and SpringerLink. </em></p> <p><em><strong>Result: </strong>A total of 1,161 articles were retrieved from online databases (PubMed, SagePub, and SpringerLink). After three rounds of screening, five articles directly relevant to the systematic review were selected for full-text reading and analysis. </em></p> <p><em><strong>Conclusion:</strong> Perinatal depression (PND) affects numerous women during and after childbirth, influenced by socioeconomic, psychosocial, and environmental factors like poverty, social support, pregnancy loss, and urban living. Early detection and comprehensive interventions are crucial to support at-risk mothers, promoting better mental health outcomes for both them and their families. </em></p>
2024-03-26T00:00:00+00:00Copyright (c) 2024 Artha Investari Nugraheni, Dini Amelia Rahmah, Wahyu Agus Prastyo, Ririn Azhari, Bella Merisa L, Astrid Ananda, Afdila Syarfinahttps://nnpub.org/index.php/MHS/article/view/2168THE EFFECT OF YOGA ON SLEEP QUALITY AND INSOMNIA IN WOMEN WITH SLEEP PROBLEMS : A SYSTEMATIC REVIEW2024-03-26T11:52:11+00:00Artha Investari NugraheniDini Amelia RahmahWahyu Agus PrastyoRirin AzhariBella Merisa LAstrid AnandaAfdila Syarfina
<p><strong><em>Background:</em></strong><em> </em><em>With prevalence estimates ranging from 4% to over 20% of the adult population, insomnia is the most prevalent sleep complaint and a serious public health problem. Yoga has also been utilized therapeutically since it is thought that various styles of yoga might have distinct psychophysiological effects.</em></p> <p><strong><em>Aims : </em></strong><em>This systematic review is to review the effect of yoga on sleep quality and insomnia in women with sleep problem.</em></p> <p><strong><em>Methods: </em></strong><em>This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. </em></p> <p><strong><em>Result: </em></strong><em>In the PubMed database, the results of our search brought up 33 articles, whereas the results of our search on SAGEPUB brought up 416 articles, our search on SCIENCE DIRECT brought up 1107 articles. The results of the search conducted for the last year of 2014 yielded a total 26 articles for PubMed, 265 articles for SAGEPUB and 684 articles for SCIENCE DIRECT. In the end, we compiled a total of 7 papers, 4 of which came from PubMed, 1 of which came from SAGEPUB and 2 of which came from SCIENCE DIRECT. We included seven research that met the criteria.</em></p> <p><strong><em>Conclusion:</em></strong><em> </em><em>In summary, </em><em>when compared to non-active control settings, yoga intervention can help women manage their sleep issues in either pregnant women, worker, or women with disease.</em></p>
2024-03-26T00:00:00+00:00Copyright (c) 2024 Artha Investari Nugraheni, Dini Amelia Rahmah, Wahyu Agus Prastyo, Ririn Azhari, Bella Merisa L, Astrid Ananda, Afdila Syarfinahttps://nnpub.org/index.php/MHS/article/view/2167THE RELATIONSHIP BETWEEN STRESS, ANXIETY, DEPRESSION AND MEDICATION ADHERENCE BEHAVIOR IN PATIENTS WITH EPILEPSY : A SYSTEMATIC REVIEW2024-03-26T11:38:35+00:00Azda Aulia FajriBudi HartonoDeby Priscika Putri Ririn AzhariBella Merisa LAstrid AnandaAfdila Syarfina
<p><strong><em>Background:</em></strong><em> </em><em>While epilepsy is a disorder characterized by unprovoked seizures, epileptic status refers to recurrent seizures without any improvement in between episodes or seizure activity that does not improve on its own.</em></p> <p><strong><em>Aims : </em></strong><em>This systematic review is to review the association of stress, anxiety, depression and medication adherence behavior in patients with epilepsy.</em></p> <p><strong><em>Methods: </em></strong><em>This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. </em></p> <p><strong><em>Result: </em></strong><em>In the PubMed database, the results of our search brought up 415 articles, whereas the results of our search on SAGEPUB brought up 573 articles, our search on SCIENCE DIRECT brought up 600 articles. The results of the search conducted for the last year of 2014 yielded a total 285 articles for PubMed, 275 articles for SAGEPUB and 391 articles for SCIENCE DIRECT. In the end, we compiled a total of 5 papers, 3 of which came from PubMed, 1 of which came from SAGEPUB and 1 of which came from SCIENCE DIRECT. We included five research that met the criteria.</em></p> <p><strong><em>Conclusion:</em></strong><em> </em><em>In summary, the anxiety, stress or depression can be the appear at epilepsy patients as the absence of the adherence of epilepsy therapeutic.</em></p>
2024-03-26T00:00:00+00:00Copyright (c) 2024 Azda Aulia Fajri, Budi Hartono, Deby Priscika Putri, Ririn Azhari, Bella Merisa L, Astrid Ananda, Afdila Syarfinahttps://nnpub.org/index.php/MHS/article/view/2166EFFECT OF THERAPEUTIC ULTRASOUND FOR NECK PAIN : A SYSTEMATIC REVIEW2024-03-26T11:28:20+00:00Wahyu Agus PrastyoArtha Investari NugraheniRirin AzhariBella Merisa LYosie Yulanda PutraAstrid AnandaAfdila Syarfina
<p><strong><em>Background:</em></strong><em> </em><em>The fourth most common cause of disability is neck discomfort, which affects more than 30% of people annually. The majority of acute neck pain episodes will go away with or without therapy, but about 50% of people will still have discomfort or recurrences on a regular basis. </em></p> <p><strong><em>Aims : </em></strong><em>This systematic review is to review the effect of therapy with ultrasound for neck pain.</em></p> <p><strong><em>Methods: </em></strong><em>This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. </em></p> <p><strong><em>Result: </em></strong><em>In the PubMed database, the results of our search brought up 5375 articles, whereas the results of our search on SAGEPUB brought up 7781 articles, our search on SCIENCE DIRECT brought up 30045 articles. The results of the search conducted for the last year of 2014 yielded a total 2864 articles for PubMed, 3376 articles for SAGEPUB and 13342 articles for SCIENCE DIRECT. In the end, we compiled a total of 7 papers, 5 of which came from PubMed, 1 of which came from SAGEPUB and 1 of which came from SCIENCE DIRECT. We included seven research that met the criteria.</em></p> <p><strong><em>Conclusion:</em></strong><em> </em><em>In summary, </em><em>therapeutic ultrasonography is a safe treatment that has the potential to lessen pain intensity more than sham or no treatment at all. It is unclear if using therapeutic ultrasonography in addition to other traditional therapies reduced pain, increased disability, or improved quality of life.</em></p>
2024-03-26T00:00:00+00:00Copyright (c) 2024 Wahyu Agus Prastyo, Artha Investari Nugraheni, Ririn Azhari, Bella Merisa L, Yosie Yulanda Putra, Astrid Ananda, Afdila Syarfinahttps://nnpub.org/index.php/MHS/article/view/2165THE ROLE OF INTIMA-MEDIA-THICKNESS, ANKLE BRACHIAL-INDEX, AND INFLAMMATORY BIOCHEMICAL PARAMETERS FOR STROKE RISK PREDICTION: AN UPDATE SYSTEMATIC REVIEW2024-03-26T11:16:14+00:00Azda Aulia FajriBudi HartonoDeby Priscika PutriRirin AzhariBella Merisa LAstrid AnandaAfdila Syarfina
<p><strong><em>Background:</em></strong><em> Stroke is a leading cause of global mortality and morbidity. The capacity to precisely estimate a person's risk of having a stroke is critical for early intervention and prevention stretegies. Researchers are exploring novel predictors beyond traditional risk factors, such as Intima-Media Thickness (IMT), Ankle-Brachial Index (ABI), and inflammatory biochemical parameters, to accurately predict stroke risk. </em></p> <p><em><strong>The aim:</strong> This study aims to determine the role of intima-media-thickness, ankle-brachial-index, and inflammatory biochemical parameters for stroke risk prediction. </em></p> <p><em><strong>Methods:</strong> By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SAGEPUB, and ScienceDirect, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. </em></p> <p><em><strong>Results:</strong> </em><em>In the PubMed database, the results of our search brought up 1,004 articles, whereas the results of our search on SAGEPUB brought up 651 articles, and our search on ScienceDirect</em><em> brought up 4,254 articles. In the end, we compiled 12 papers, 8 of which came from PubMed, 1 of which came from SAGEPUB, and 3 of which came from ScienceDirect</em><em>. We included twelve research that met the criteria.<strong> </strong></em></p> <p><em><strong>Conclusion:</strong> In conclusion, the findings of our study strongly support that Carotid Intima-Media Thickness (CIMT) and Ankle-Brachial Index (ABI) hold significant promise as predictors of stroke risk. This can be helpful to improve stroke prevention and management strategies. However, further research is warranted to clarify the role of inflammatory biochemical parameters in the context of stroke risk prediction.</em></p>
2024-03-26T00:00:00+00:00Copyright (c) 2024 Azda Aulia Fajri, Budi Hartono, Deby Priscika Putri, Ririn Azhari, Bella Merisa L, Astrid Ananda, Afdila Syarfinahttps://nnpub.org/index.php/MHS/article/view/2162PRATIQUE D’AUTOMEDICATION AU MANIEMA, APPROCHES INTERACTIVE ET INCLUSIVE D’EDUCATION SANITAIRE EN MILIEU ACADEMIQUE2024-03-26T06:46:03+00:00Docteur Mathieu Ngengele Kangela
<p><em>Cet article sur l’automédication au MANIEMA approche interactive et inclusive d’éducation sanitaire dans le milieu académique , une étude menée dans la province du MANIEMA plus précisément dans la ville de Kindu au sein l’institut supérieur des sciences de la santé de Kindu sur un effectif de 120 étudiants ayant répondu à une interview guidée dont le traitement des données se fait grâce à l’analyse statistique descriptive ( Fréquence, proportion , moyenne) . Apres analyse il ressort que suit : que le genre féminin occupe 60 de nos enquêtes, la tranche d’âge de 17B à 25 ans est plus dominante avec 61,6, la commune rurale d’Alunguli est le lieu de provenance de la majorité d’étudiants avec 41,6. Pour ce qui est des causes ou la motivation d’usage de la pratique de l’automédication dont nombreux ont avoué que cette pratique devient de plus en plus dangereuse au besoin constitue un problème de santé publique dans le milieu universitaire selon nos enquêtes la première cause est le niveau socio-économique bas qui fait les étudiants sont incapables de prendre en charge les frais de consultation et cela à une proportion de 62,5 , en deuxième position vient la banalisation de certaines pathologies habituelles dont les schémas sont supposées connus telles que : le paludisme , les infections …(23,3) et troisième position vient l’absence des structures sanitaires fiables dans le milieu universitaire. Par rapport aux médicaments que les étudiants avouent avoir pris sans aucune prescription médicale en première viennent les anti-inflammatoires ayant deux ou plusieurs propriétés pharmacocinétiques à la hauteur de 45, la combinaison des antiinflammatoires, antipaludéens et les antibiotiques vient en deuxième position 23,33, les antipaludéens seuls prennent la troisième avec 19,16 et en quatrième position ce sont les antibiotiques 12,5.En fin par rapport aux inconvénients liés à l’automédication l’induction des nouvelles pathologies et l’exacerbation des anciennes occupent la première(39,16 telle que la gastrite) , deuxième position vient la résistance microbienne (37,5) et troisième position viennent les erreurs thérapeutiques ou celles de diagnostic (23,33).</em></p>
2024-03-26T00:00:00+00:00Copyright (c) 2024 Docteur Mathieu Ngengele Kangelahttps://nnpub.org/index.php/MHS/article/view/2161PALUDISME GRAVE CHEZ LES ENFANTS DE 0 A 5 ANS : CARACTERISTIQUES SOCIODEMOGRAPHIQUES, COUT ET PRISE EN CHARGE AU 4 DECEMBRE 20232024-03-26T06:40:19+00:00Docteur Mathieu Ngengele Kangela
<p><em>Le paludisme est l’une des plus fréquentes maladies infectieuses. Il pose un problème sanitaire</em><em> public important partout dans le monde, tout particulièrement en Afrique et en Asie du Sud. Quelque trois milliards de personnes sont exposées à des risques d’infections dans 109 pays. Les principaux faits qui ont marqué les différentes années sont présentés de la manière suivante : En 2022 , on estime à 249 millions de cas de paludisme et à 608000 le nombre de décès dus au paludisme dans 85 pays , la Région africaine de l’OMS supporte une importante et disproportionnée de la charge mondiale du paludisme ,En 2022 ,94 des cas de paludisme (233millions) et 95% des décès dus à la maladie (580000) ont été enregistrés dans cette région , les enfants de moins de cinq ans représentaient 80% des décès dus au paludisme dans la région ( selon Selon le programme national de lutte contre le paludisme , la RDC porte le poids le plus lourd du paludisme dans le monde soit 40 après le Nigeria ces différents de de l’OMS, du PNLP et notre propre expérience dans les structures sanitaires ont motivé notre curiosité scientifique pour faire une étude sur le paludisme grave chez les enfants en tenant compte des caractéristiques sociodémographiques, le cout et sa prise charge .</em></p>
2024-03-26T00:00:00+00:00Copyright (c) 2024 Docteur Mathieu Ngengele Kangelahttps://nnpub.org/index.php/MHS/article/view/2160MANAGEMENT OF HELLP SYNDROME BEFORE DELIVERY: A COMPREHENSIVE SYSTEMATIC REVIEW2024-03-23T07:25:09+00:00Roy ChristianFrenki Pieter HethariaFranky Bangkit SumardiInggit Dwi Rahayu
<p><strong><em>Background:</em></strong><em> </em><em>HELLP syndrome, a rare and serious complication during pregnancy, poses significant risks to both mother and fetus. Early management of HELLP syndrome before delivery may improve the outcomes for </em><em>patients</em><em>.</em><em> </em><em>This study aims to systematically review literatures on HELLP syndrome management before delivery in the last 10 years. </em></p> <p><em><strong>Methods: </strong>This systematic review complied with the PRISMA 2020 standards and focused on full-text English literature published between 2014 and 2024. Articles such as editorials and review papers from the same journal, as well as submissions lacking a DOI, were excluded from consideration. Literature was sourced from online platforms like PubMed and SagePub. </em></p> <p><em><strong>Result: </strong>We found 1629 articles on PubMed and 560 articles on SagePub. Restricting our search to the past decade (2014-2024), PubMed presented 507 articles, whereas SagePub presented 288 articles. From these, we selected 5 papers meeting our criteria, with 3 from PubMed and 2 from SagePub. </em></p> <p><em><strong>C</strong></em><em><strong>onclusion:</strong> </em><em>The main treatment approach for HELLP syndrome involves stabilizing the mother and ensuring timely delivery. Various strategies, including the use of corticosteroids and glucocorticoids, have been explored to reduce the associated morbidity and mortality. </em></p>
2024-03-23T00:00:00+00:00Copyright (c) 2024 Roy Christian, Frenki Pieter Hetharia, Franky Bangkit Sumardi, Inggit Dwi Rahayuhttps://nnpub.org/index.php/MHS/article/view/2159UTERINE RUPTURE DURING PREGNANCY: A COMPREHENSIVE SYSTEMATIC REVIEW2024-03-23T07:17:46+00:00Roy ChristianFrenki Pieter HethariaFranky Bangkit SumardiInggit Dwi Rahayu
<p><em><strong>Introduction:</strong> Uterine rupture, a rare but serious obstetric condition involving a tear through the uterine wall, has varying incidences globally, with scarred uteri, morbidly attached placenta, grand multiparity, and oxytocin use being common risk factors. This systematic review aims to comprehensively analyze the literature on uterine rupture during pregnancy, focusing on risk factors, geographical incidence variations, etiological patterns, impact of medical interventions, and maternal outcomes, with a goal to enhance understanding, identify preventive strategies, and improve clinical management. </em></p> <p><em><strong>Method:</strong> The researchers in this study followed the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines to ensure that their work met the required standards. This was done to ensure the precision and reliability of the conclusions derived from the research.<strong> </strong></em></p> <p><em><strong>Result:</strong> Our search produced 11 results. After looking at the titles and summaries, we found 9 papers that fit our criteria. At first, we excluded several articles because they were written in review style and case reports. But after reading the full papers carefully, we included five papers in our final analysis. These papers included a retrospective observational study, prospective study, and retrospective study. </em></p> <p><em><strong>Conclusion: </strong>In conclusion, uterine rupture (UR) is a catastrophic event requiring heightened vigilance in pregnant women with high-risk factors to mitigate severe consequences for both obstetricians and patients. Trials of labor after cesarean (TOLAC), a safe delivery option, faces challenges in Shanghai and China, and the risk of uterine rupture emphasizes the need for evaluating dosages and duration of prostaglandins and oxytocin. Our series highlights the grave neonatal prognosis of uterine rupture, stressing the importance of timely management and recognizing fetal heart rate abnormalities. The URIDA investigation, the largest database on UR during pregnancy, reveals insights into the association between previous uterine surgery, leiomyoma, and UR, emphasizing the need for early diagnosis and immediate treatment to minimize complications and ensure favorable outcomes in both the index and subsequent pregnancies. </em></p>
2024-03-23T00:00:00+00:00Copyright (c) 2024 Roy Christian, Frenki Pieter Hetharia, Franky Bangkit Sumardi, Inggit Dwi Rahayuhttps://nnpub.org/index.php/MHS/article/view/2158ASSOCIATION OF CIGARETTE SMOKING AND RISK OF URINARY BLADDER CANCER : A SYSTEMATIC REVIEW2024-03-22T07:01:47+00:00Bayu KusumoInannami Fadiyah Mahrunnisa
<p><strong><em>Background:</em></strong><em> </em><em>It has been proposed that smoking cigarettes increases the likelihood of urinary bladder cancer (UBCa). But not everyone who smokes heavily gets these illnesses, and first-degree relatives' higher cancer risk points to a significant hereditary component.</em></p> <p><strong><em>Aims : </em></strong><em>This systematic review is to review the association between cigarette smoking and its risk of urinary bladder cancer in men and women.</em></p> <p><strong><em>Methods: </em></strong><em>This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. </em></p> <p><strong><em>Result: </em></strong><em>In the PubMed database, the results of our search brought up 729 articles, whereas the results of our search on SAGEPUB brought up 1495 articles, our search on SCIENCE DIRECT brought up 11284 articles. The results of the search conducted for the last year of 2014 yielded a total 177 articles for PubMed, 442 articles for SAGEPUB and 3775 articles for SCIENCE DIRECT. In the end, we compiled a total of 8 papers, 5 of which came from PubMed, 1 of which came from SAGEPUB and 2 of which came from SCIENCE DIRECT. We included eight research that met the criteria.</em></p> <p><strong><em>Conclusion:</em></strong><em> </em><em>In summary, </em><em>tobacco smoking was a strong risk factor for bladder cancer for both men and women.</em></p>
2024-03-22T00:00:00+00:00Copyright (c) 2024 Bayu Kusumo, Inannami Fadiyah Mahrunnisahttps://nnpub.org/index.php/MHS/article/view/2157PERIOPERATIVE ANTIBIOTIC PROPHYLAXIS IN UROLOGICAL SURGERY: AN UPDATE SYSTEMATIC REVIEW2024-03-22T06:55:55+00:00Bayu KusumoInannami Fadiyah Mahrunnisa
<p><strong><em>Background: </em></strong><em>Perioperative antibiotic prophylaxis (PAP) is provided to avoid local or systemic infections, such as surgical site infections (SSI), urinary tract infections (UTI), or sepsis. However, PAP may not be effective in reducing symptomatic UTI in some procedures, such as extracorporeal shock wave lithotripsy and cystoscopy. </em></p> <p><em><strong>The aim:</strong> This study aims to determine the effectiveness of perioperative antibiotic prophylaxis in urological surgery. </em></p> <p><em><strong>Methods:</strong> By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SAGEPUB, and ScienceDirect, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. </em></p> <p><em><strong>Results:</strong> </em><em>In the PubMed database, the results of our search brought up 105 articles, whereas the results of our search on SAGEPUB brought up 6 articles, our search on </em><em>ScienceDirect</em><em> brought up 129 articles. In the end, we compiled 9 papers, 7 of which came from PubMed, and 2 of which came from </em><em>ScienceDirect</em><em>. We included nine research that met the criteria.</em><strong><em> </em></strong></p> <p><strong><em>Conclusion:</em></strong><em> Perioperative antibiotic prophylaxis (PAP) can lower SSI, UTI, and sepsis incidences in urological surgery. In addition, PAP showed a lower positive blood culture. To minimize side effects and lower the risk of drug-resistant organisms, the use of reasonable PAP is advised. </em></p>
2024-03-22T00:00:00+00:00Copyright (c) 2024 Bayu Kusumo, Inannami Fadiyah Mahrunnisahttps://nnpub.org/index.php/MHS/article/view/2156BREAKFAST SKIPPING IS ASSOCIATED WITH INCREASED RISK OF TYPE 2 DIABETES AMONG ADULTS : A SYSTEMATIC REVIEW2024-03-22T06:47:51+00:00Ilma FitrianaDela Intan Permatasari
<p><strong><em>Background:</em></strong><em> While certain lifestyle habits may be associated with arterial stiffness, there is limited literature investigating the relationship between lifestyle habits and longitudinal changes in arterial stiffness in patients with type 2 diabetes mellitus (T2DM).</em></p> <p><strong><em>Aims : </em></strong><em>This systematic review is to review the association of breakfast skipping and the risk of type 2 diabetes in adults</em><strong><em>.</em></strong></p> <p><strong><em>Methods: </em></strong><em>This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. </em></p> <p><strong><em>Result: </em></strong><em>In the PubMed database, the results of our search brought up 569 articles, whereas the results of our search on SAGEPUB brought up 2731 articles, our search on SCIENCE DIRECT brought up 1382 articles. The results of the search conducted for the last year of 2014 yielded a total 335 articles for PubMed, 1173 articles for SAGEPUB and 864 articles for SCIENCE DIRECT. In the end, we compiled a total of 7 papers, 4 of which came from PubMed, 1 of which came from SAGEPUB and 2 of which came from SCIENCE DIRECT. We included seven research that met the criteria.</em></p> <p><strong><em>Conclusion:</em></strong><em> </em><em>In summary,</em><em> </em><em>breakfast skipping is associated in increasing of type 2 diabetes in adults but also need more studies because the studies of this topic is limited and less reported.</em></p>
2024-03-22T00:00:00+00:00Copyright (c) 2024 Ilma Fitriana, Dela Intan Permatasarihttps://nnpub.org/index.php/MHS/article/view/2155UPDATE ON THE RELATIONSHIP BETWEEN VITAMIN D AND DEPRESSION: SYSTEMATIC REVIEW2024-03-22T06:15:46+00:00Ilma FitrianaDela Intan Permatasari
<p><strong><em>Introduction: </em></strong><em>Depression remains a significant global health challenge, affecting approximately one in ten individuals, and its multifaceted nature requires prolonged therapeutic interventions. Recent studies have explored the potential link between vitamin D deficiency and depression, highlighting the role of vitamin D in neurobiology and its plausible association with depressive symptoms. However, the exact nature of this relationship and its implications for depression management require further investigation, as outlined in the systematic review "Association of Vitamin D and Depression: An Update Systematic Review," aiming to provide clarity on the role of vitamin D in depression etiology and guide future research and clinical interventions. </em></p> <p><em><strong>Method: </strong>The researchers in this study followed the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines to ensure that their work met the required standards. This was done to ensure the precision and reliability of the conclusions derived from the research.</em><em> </em></p> <p><strong><em>Result: </em></strong><em>Our search produced 13 results. After looking at the titles and summaries, we found 10 papers that fit our criteria. At first, we excluded several articles because they were written in review style and case reports. But after reading the full papers carefully, we included five papers in our final analysis. These papers included </em><em>experimental study, observational study a randomized, double-blind, placebo controlled clinical trial, a cross-sectional analysis, and double-blind randomized clinical trial.<strong> </strong></em></p> <p><em><strong>Conclusion</strong>: Some studies indicate improvements in mood, reductions in corticosterone levels, and prevention of serum vitamin D decreases with vitamin D and SSRI antidepressant combination. Another study in obese women with depression showed positive effects on mood, BDNF levels, inflammation, and SIRT1 with vitamin D and magnesium supplementation. However, no significant associations were found between baseline vitamin D levels and depression symptoms, and vitamin D supplementation did not improve depression symptoms in deficient but otherwise healthy individuals, suggesting caution in using it for depression management. Further research, especially in diverse populations, is needed to clarify the role of vitamin D in depression.</em></p>
2024-03-22T00:00:00+00:00Copyright (c) 2024 Ilma Fitriana, Dela Intan Permatasarihttps://nnpub.org/index.php/MHS/article/view/2154ASSOCIATION OF CALCIUM DIETARY WITH BODY MASS INDEX AND BODY FAT : A SYSTEMATIC REVIEW2024-03-22T06:08:42+00:00Ilma FitrianaDela Intan Permatasari
<p><strong><em>Background:</em></strong><em> </em><em>When consuming the necessary amounts of calcium, body mass index (BMI) rises with calcium retention. </em></p> <p><strong><em>Aims : </em></strong><em>This systematic review is to review the association of calcium diet with body mass index and body fat.</em></p> <p><strong><em>Methods: </em></strong><em>This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. </em></p> <p><strong><em>Result: </em></strong><em>In the PubMed database, the results of our search brought up 1195 articles, whereas the results of our search on SAGEPUB brought up 14152 articles, our search on SCIENCE DIRECT brought up 21833 articles. The results of the search conducted for the last year of 2014 yielded a total 536 articles for PubMed, 5253 articles for SAGEPUB and 10269 articles for SCIENCE DIRECT. In the end, we compiled a total of 8 papers, 5 of which came from PubMed, 1 of which came from SAGEPUB and 2 of which came from SCIENCE DIRECT. We included eight research that met the criteria.</em></p> <p><strong><em>Conclusion:</em></strong><em> </em><em>In summary,</em><em> </em><em>from eight studies showed that there is no significant changed of body mass index, neither the body fat after received the dietary of calcium.</em></p>
2024-03-22T00:00:00+00:00Copyright (c) 2024 Ilma Fitriana, Dela Intan Permatasarihttps://nnpub.org/index.php/MHS/article/view/2153STUNTING PREVENTION STRATEGY BY IMPROVING THE NUTRITIONAL STATUS OF TODDLER : A SYSTEMATIC REVIEW2024-03-22T06:01:36+00:00Ilma FitrianaDela Intan Permatasari
<p><em><strong>Background:</strong> Globally, there has been progress in lowering the rates of linear growth stunting and chronic undernutrition in children under five years old, however many areas still have high rates.</em></p> <p><em><strong>Aims : </strong>This systematic review is to review stunting prevention strategy with improving status of nutrition in toddler.</em></p> <p><em><strong>Methods: </strong>This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included.</em></p> <p><em><strong>Result: </strong>In the PubMed database, the results of our search brought up 691 articles, whereas the results of our search on SAGEPUB brought up 2026 articles, our search on SCIENCE DIRECT brought up 4136 articles. The results of the search conducted for the last year of 2014 yielded a total 430 articles for PubMed, 776 articles for SAGEPUB and 2307 articles for SCIENCE DIRECT. In the end, we compiled a total of 8 papers, 6 of which came from PubMed, 1 of which came from SAGEPUB and 1 of which came from SCIENCE DIRECT. We included eight research that met the criteria.</em></p> <p><em><strong>Conclusion:</strong> In summary, stunting must be managed in order to protect children from its harmful effects. To do this, a variety of linked parties must contribute to the effort. Improving the mother's responsive stimulation and health education might be the first step in improving the nutritional and cognitive state of the kid.</em></p>
2024-03-22T00:00:00+00:00Copyright (c) 2024 Ilma Fitriana, Dela Intan Permatasarihttps://nnpub.org/index.php/MHS/article/view/2152UPDATE ON MICRONUTRIENTS IN BARIATRIC SURGERY: A COMPREHENSIVE SYSTEMATIC REVIEW2024-03-22T05:46:24+00:00Ilma FitrianaDela Intan Permatasari
<p><strong><em>Background:</em></strong><em> </em><em>Obesity is a major problem in the world and bariatric surgery is an effective solution for weight loss and resolving related health issues. There are three different types of bariatric surgeries. However, nutritional imbalances are a common issue after these procedures. Therefore, individuals who opt for bariatric surgery require continuous monitoring of their micronutrient levels and ongoing supplementation. This study aims to serve as a comprehensive systematic review of updates on micronutrients in bariatric surgery in the literature of the last 10 years. </em></p> <p><strong><em>Methods: </em></strong><em>This review adhered to the PRISMA 2020 guidelines and analyzed English literature published between 2014 and 2024, inclusive of full-text articles. Articles such as editorials, review papers from the same journal, and those without a DOI were not included in the review. The literature was obtained from various online platforms, including PubMed, SagePub, and Science Direct. </em></p> <p><em><strong>Result: </strong>Our team of researchers initially collected 3165 articles from credible sources that included PubMed, SagePub, and Science Direct. Following a rigorous three-level screening process, only six articles were found to be directly relevant to our ongoing systematic review and were then selected for further analysis through thorough full-text reading. </em></p> <p><em><strong>Conclusion:</strong> Bariatric surgery, especially RYGB, can cause micronutrient deficiencies. Vitamin deficiencies (A, D) are common and iron deficiency anemia is prevalent. Zinc, copper, and selenium deficiencies can also occur. Regular supplement intake is crucial to maintain optimal micronutrient levels.</em></p>
2024-03-22T00:00:00+00:00Copyright (c) 2024 Ilma Fitriana, Dela Intan Permatasarihttps://nnpub.org/index.php/MHS/article/view/2151THE IMPACT OF DAIRY CONSUMPTION ON WEIGHT FLUCTUATIONS AND OBESITY RISK THROUGHOUT MENOPAUSE: A COMPREHENSIVE SYSTEMATIC REVIEW2024-03-22T05:40:09+00:00Ilma FitrianaDela Intan Permatasari
<p><strong><em>Introduction: </em></strong><em>The perimenopausal transition poses significant physiological changes and an elevated risk of obesity among women, with studies demonstrating weight gain and metabolic disruptions during this phase. Dairy products, recommended in the typical diet, remain contentious in their impact on weight despite their nutrient-rich composition. Our systematic review aims to address this uncertainty by synthesizing existing evidence on the association between dairy consumption, weight change, and obesity risk during the menopausal transition, shedding light on the nuanced effects of different dairy products and informing tailored dietary interventions for optimal health during this critical life stage.<strong> </strong></em></p> <p><em><strong>Method: </strong></em><em>The researchers in this study followed the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines to ensure that their work met the required standards. This was done to ensure the precision and reliability of the conclusions derived from the research.</em><em> </em></p> <p><strong><em>Result: </em></strong><em>This systematic review investigated final 20 articles. After looking at the titles and summaries, we found 10 papers that fit our criteria. At first, we excluded several articles because they were written in review style and case reports. But after reading the full papers carefully, we included five papers in our final analysis. These papers included analytical cohort, randomized, crossover study, and prospective study. </em></p> <p><em><strong>Conclusion</strong>: In conclusion, incorporating yogurt into the diet may benefit perimenopausal women by reducing weight gain and obesity risk, but further investigation is needed to understand the underlying mechanisms. Additionally, controlled-feeding studies showed limited effects of short-term consumption of 2 fat milk on cardiometabolic risk factors in postmenopausal women with abdominal obesity, raising questions about disparities with epidemiological findings associating dairy consumption with reduced risk of metabolic disorders. Longitudinal cohort studies found no evidence supporting the beneficial effects of dairy intake on bone health in middle-aged women, while higher total dairy intake, mainly from high-fat sources, was associated with less weight gain over time in women with normal BMI at baseline. Further well-powered trials are needed to comprehensively understand dairy's role in preventing weight gain and obesity across different life stages.</em></p>
2024-03-22T00:00:00+00:00Copyright (c) 2024 Ilma Fitriana, Dela Intan Permatasarihttps://nnpub.org/index.php/MHS/article/view/2146EFFECTS OF VITAMIN D IN NEONATES AND YOUNG INFANTS: AN UPDATED SYSTEMATIC REVIEW2024-03-19T05:19:52+00:00Grace ErdianaGlenardi
<p><strong><em>Background:</em></strong><em> </em><em>Vitamin D is a fat-soluble vitamin essential for calcium metabolism, maintaining calcium homeostasis, and supporting skeletal mineralization. Low maternal levels of vitamin D during pregnancy are linked to various adverse neonatal outcomes. </em><em>This study aims to systematically review the effects of Vitamin D in neonates and infants in literatures of the last 5 years. </em></p> <p><em><strong>Methods: </strong>The systematic review followed PRISMA 2020 standards and examined full-text English literature published between 2019 and 2024. This review excluded editorials, review papers from the same journal, and submissions without a DOI. Literature was sourced from online platforms such as PubMed, SagePub, SpringerLink, and Google Scholar. </em></p> <p><em><strong>Result: </strong>A total of 2,866 articles were retrieved from online databases (PubMed, SagePub, SpringerLink and Google Scholar). After three rounds of screening, four articles directly relevant to the systematic review were selected for full-text reading and analysis. </em></p> <p><em><strong>Conclusion:</strong> Vitamin D is essential for skeletal, immune, and neurodevelopmental health in children. Maternal supplementation during pregnancy is crucial for ensuring adequate levels in infants and neonates, along with promoting sunlight exposure and dietary intake, particularly in regions with high rates of maternal vitamin D deficiency.</em></p>
2024-03-19T00:00:00+00:00Copyright (c) 2024 Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)https://nnpub.org/index.php/MHS/article/view/2139EPIDEMIOLOGY AND RISK FACTORS FOR COLORECTAL RECTAL CANCER: AN UPDATE SYSTEMATIC REVIEW2024-03-15T07:17:28+00:00Supriyadi GajahJohannes Martupa Lumbantoruan
<p><strong><em>Background:</em></strong><em> </em><strong><em> </em></strong><em>The global burden of colorectal cancer (CRC) has been rising rapidly with population growth, changes in demographics and Westernization of lifestyle habits. It was estimated to have 18.1 million new cancer cases, and 9.6 million deaths caused by cancer in year 2018. CRC is the third commonest diagnosed cancer and the second leading cause of cancer-related mortality. According to the World Health Organization (WHO) GLOBOCAN database, there are 1,849,518 estimated new CRC cases and 880,792 CRC-related deaths in 2018. Regional estimates show that among half of the new cases, deaths and 5-year prevalent cases were found in Asia. </em></p> <p><strong><em>The aim:</em></strong><em> The aim of this study to show about epidemiology and risk factors for colorectal cancer.<strong> </strong></em></p> <p><em><strong>Methods: </strong>By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Google Scholar were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. </em></p> <p><em><strong>Result: </strong>In the PubMed database, the results of our search get 41 articles, whereas the results of our search on SagePub get 151 articles, on Google Scholar 2598 articles. </em><em>Records remove before screening are 800, so we get 1990 articles fos screening</em><em>. After we screened based on record exclude, we compiled a total of 12 papers. We included five research that met the criteria. </em></p> <p><em><strong>Conclusion: </strong></em><em>Colorectal cancer is effectively preventable through primary and secondary prevention. Environmental risk factor mediation by the provision of information and encouragement of healthy behaviors, while striving for early diagnosis through appropriate screening tests, can lead to a reduction in the stagnant incidence and mortality rates.</em></p>
2024-03-15T00:00:00+00:00Copyright (c) 2024 Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)https://nnpub.org/index.php/MHS/article/view/2138EARLY OPERATIVE MANAGEMENT OF COMPLICATED APPENDICITIS IS ASSOCIATED WITH IMPROVED SURGICAL OUTCOMES IN ADULTS: A COMPREHENSIVE SYSTEMATIC REVIEW2024-03-15T07:06:34+00:00Supriyadi GajahJohannes Martupa Lumbantoruan
<p><strong><em>Background: </em></strong><em>The management of appendicitis has been surgical over the years with high significant efficacy and low complication rate, and is recommended for the treatment of appendicitis in those cases in which there is a dilatation of more than 13 mm of the appendix, mass effect or presence of appendicolith in imaging. However, recent evidence from different series has proposed medical management for this condition in specific high surgical risk populations.</em><strong><em> </em></strong></p> <p><strong><em>The aim:</em></strong><em> The aim of this study to show about<strong> </strong>early operative management of complicated appendicitis is associated with improved surgical outcomes in adults. </em></p> <p><em><strong>Methods: </strong>By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Google Scholar were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. </em></p> <p><em><strong>Result: </strong>In the PubMed database, the results of our search get 23 articles, whereas the results of our search on SagePub get 151 articles, on Google Scholar 2840 articles. </em><em>Records remove before screening are 2110, so we get 904 articles fos screening</em><em>. After we screened based on record exclude, we compiled a total of 10 papers. We included five research that met the criteria. </em></p> <p><em><strong>Conclusion: </strong></em><em>Laparoscopic appendicectomy is becoming the gold standard for the treatment of appendicitis. However, the advantages of the innovations in minimally invasive and endoscopic surgery are unlikely to render formal open appendicectomy obsolete. Nonoperative management with antibiotics may suffice in selected cases with uncomplicated appendicitis.</em></p>
2024-03-15T00:00:00+00:00Copyright (c) 2024 Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)https://nnpub.org/index.php/MHS/article/view/2137DIAGNOSIS AND MANAGEMENT OF HEMORRHOIDS : A SYSTEMATIC REVIEW2024-03-15T06:55:50+00:00Supriyadi GajahJohannes Martupa Lumbantoruan
<p><strong><em>Background:</em></strong><em> </em><em>Hemorrhoids are vascular tissues that naturally develop in the submucosa of the anal canal. They are composed of blood vessels with many arteriovenous connections, smooth muscle, and loose connective tissue, which explains why hemorrhoidal bleeding is usually brilliant red.</em></p> <p><strong><em>Aims : </em></strong><em>This systematic review is to review the diagnosis and managements of hemorrhoids</em><strong><em>.</em></strong></p> <p><strong><em>Methods: </em></strong><em>This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. </em></p> <p><strong><em>Result: </em></strong><em>In the PubMed database, the results of our search brought up 7536 articles, whereas the results of our search on SAGEPUB brought up 4560 articles, our search on SCIENCE DIRECT brought up 5110 articles. The results of the search conducted for the last year of 2014 yielded a total 3250 articles for PubMed, 1369 articles for SAGEPUB and 1565 articles for SCIENCE DIRECT. In the end, we compiled a total of 8 papers, 5 of which came from PubMed, 1 of which came from SAGEPUB and 2 of which came from SCIENCE DIRECT. We included eight research that met the criteria.</em></p> <p><strong><em>Conclusion:</em></strong><em> </em><em>In summary,</em><em> </em><em>the illness hemorrhoids is prevalent yet complicated. Patients who have hemorrhoidal signs and symptoms should be closely examined to rule out other possible masquerade conditions. Hemorrhoids can be managed in a variety of ways, and the best course of action depends on the unique needs of each patient as well as clinical considerations.</em></p>
2024-03-15T00:00:00+00:00Copyright (c) 2024 Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)https://nnpub.org/index.php/MHS/article/view/2134LONG-TERM RISK OF CHRONIC AND END-STAGE KIDNEY DISEASE AFTER PREECLAMPSIA: SYSTEMATIC REVIEW2024-03-13T14:24:43+00:00Mohamad Azwar AzizYulia Intan KaniaIlham AzizSibli
<p><strong><em>Introduction: </em></strong><em>Preeclampsia (PE) is a pregnancy-related syndrome, and its diagnosis has evolved to consider factors like hypertension and kidney involvement, with serum creatinine gaining importance. Despite the traditional view of PE as transient and reversible kidney disease, recent studies link it to long-term risks, including cardiovascular and renal diseases. The systematic review, "Long-Term Risk of Chronic and End-Stage Kidney Disease After Preeclampsia," aims to gather updated information from recent studies, focusing on ESRD, CKD, and kidney-related morbidity after PE. The goal is to inform the formulation of effective long-term control and prevention strategies for CKD associated with a history of preeclampsia.<strong> </strong></em></p> <p><em><strong>Method: </strong></em><em>The researchers in this study followed the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines to ensure that their work met the required standards. This was done to ensure the precision and reliability of the conclusions derived from the research.</em><em> </em></p> <p><strong><em>Result: </em></strong><em>This systematic review investigated final 16 articles. After looking at the titles and summaries, we found 8 papers that fit our criteria. At first, we excluded several articles because they were written in review style and case reports. But after reading the full papers carefully, we included five papers in our final analysis. These papers included a nation-wide cohort, nationwide register based cohort study, observational cohort study, population-based nested case-control study, and longitudinal cohort study. </em></p> <p><em><strong>Conclusion</strong>: Our study reveals a significant long-term impact of preeclampsia on kidney health, with a 5-fold higher risk of end-stage kidney disease (ESKD) for affected women. Ongoing clinical monitoring and further research are crucial to identify high-risk individuals, understand underlying mechanisms, and establish optimal follow-up and intervention strategies. </em></p>
2024-03-13T00:00:00+00:00Copyright (c) 2024 Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)https://nnpub.org/index.php/MHS/article/view/2133PREVALENCE, RISK FACTOR, MANAGEMENT AND OUTCOME OF RESISTANT HYPERTENSION: SYSTEMATIC REVIEW2024-03-13T14:16:50+00:00Mohamad Azwar AzizYulia Intan KaniaIlham AzizSibli
<p><strong><em>Background:</em></strong><em> </em><em>Resistant hypertension (RH) increases the morbidity and mortality from stroke and cardiovascular disease in comparison to hypertension without treatment resistance.</em></p> <p><strong><em>Aims : </em></strong><em>This systematic review is to review the prevalence, risk factor and management of resistant hypertension.</em></p> <p><strong><em>Methods: </em></strong><em>This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. </em></p> <p><strong><em>Result: </em></strong><em>In the PubMed database, the results of our search brought up 1032 articles, whereas the results of our search on SAGEPUB brought up 29093 articles, our search on SCIENCE DIRECT brought up 96059 articles. The results of the search conducted for the last year of 2014 yielded a total 556 articles for PubMed, 12517 articles for SAGEPUB and 43884 articles for SCIENCE DIRECT. In the end, we compiled a total of 9 papers, 4 of which came from PubMed, 1 of which came from SAGEPUB and 4 of which came from SCIENCE DIRECT. We included nine research that met the criteria.</em></p> <p><strong><em>Conclusion:</em></strong><em> </em><em>In summary,</em><em> </em><em>the therapy of lowered heart rate includes improving lifestyle modifications, utilizing long-acting thiazide-like diuretics, adding a mineralocorticoid receptor antagonist, and gradually adding antihypertensive drugs with complementary modes of action if blood pressure does not decline.</em></p>
2024-03-13T00:00:00+00:00Copyright (c) 2024 Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)https://nnpub.org/index.php/MHS/article/view/2132DIABETES MELLITUS A RISK FACTOR OF GASTRIC CANCER : SYSTEMATIC REVIEW2024-03-13T14:07:04+00:00Mohamad Azwar AzizYulia Intan KaniaIlham AzizSibli
<p><strong><em>Background:</em></strong><em> </em><em>It is estimated that 500 million individuals globally would have diabetes mellitus (DM) by 2030. A deadly tumor that affects the digestive tract is called gastric cancer (GC). It ranks as the fourth leading cause of cancer death worldwide and the fifth most common kind of cancer. Every year, there are around 700,000 fatalities and one million new cases of GC globally.</em></p> <p><strong><em>Aims : </em></strong><em>This systematic review is to review the association of diabetes mellitus as a risk factor of gastric cancer</em><strong><em>.</em></strong></p> <p><strong><em>Methods: </em></strong><em>This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. </em></p> <p><strong><em>Result: </em></strong><em>In the PubMed database, the results of our search brought up 343 articles, whereas the results of our search on SAGEPUB brought up 2178 articles, our search on SCIENCE DIRECT brought up 23102 articles. The results of the search conducted for the last year of 2014 yielded a total 231 articles for PubMed, 1017 articles for SAGEPUB and 12260 articles for SCIENCE DIRECT. In the end, we compiled a total of 5 papers, 2 of which came from PubMed, 1 of which came from SAGEPUB and 2 of which came from SCIENCE DIRECT. We included five research that met the criteria.</em></p> <p><strong><em>Conclusion:</em></strong><em> </em><em>In summary,</em><em> </em><em>there is no direct association of diabetes mellitus and gastric cancer, but diabetes mellitus can increase the risk factor of gastric cancer cases.</em></p>
2024-03-13T00:00:00+00:00Copyright (c) 2024 Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)