Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425) <p><strong>Journal of Advance Research in Medical &amp; Health Science (ISSN: 2208-2425)&nbsp;</strong>is rapidly growing journal in field of medical, biomedical, health science, primary health care, medicines, various therapies, medical instruments and latest techniques, Ayurveda etc.</p> NN Publication en-US Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425) 2208-2425 Epidemiologic and surgical approach of cranyosynostosis: case of Madagascar and review of literature <p><strong>Introduction:</strong> Craniosynostosis is a premature closure of one or more sutures of the skull. She reaches 1 child out of 2100. She is responsible for a psychomotor developmental delay. The objective of this study was to define epidemiology, surgical approach and compare with literature.</p> <p><strong>Methods</strong>: this was a multicenter retrospective descriptive study performed in hospitalized children operated or not on three neurosurgery centers (CHU-JRA, CENHOSOA and Fianarantsoa), from January 2010 to December 2017. Variables studied: epidemiology, clinical, paraclinical and therapeutic.</p> <p><strong>Results:</strong> During the targeted period, 52 children had craniosynostosis (4 cases at CENHSOA, 6 at Fianarantsoa and 42 at CHUA-HJRA). There was a clear male predominance with a sex ratio of 2.4. The average age was 13.11 months. Several types of craniosynostosis were reported, the majority of which were dominated by brachycephaly in 40.38% followed by scaphocephalia (21.15%) and 2 cases of Apert Syndrome. The main symptom was delayed psychomotor development (34.46%). A standard radiography of the skull required in 76.92% and a scanner in 15.38% of the cases. The average age at surgery was 13.04 months. The majority of the surgical techniques practiced were a suturotomy, with blood transfusion and the majority of which at the time of the incision.</p> <p><strong>Conclusion:</strong> Craniosynostosis is a pathology that requires neurosurgical management. Several operative techniques exist but the indication depends on the age and the clinico-radiological aspect of the pathology. The main cause of death is related to intraoperative bleeding.</p> <p>&nbsp;</p> Bemora Joseph Synèse Rakotondrainibe Willy Francis Andrianaivo Radotiana Tony Ratovondrainy Willy Rabararijaona Mamiarisoa Andriamamonjy Clément Copyright (c) 2019 Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425) 2019-10-16 2019-10-16 5 9 01 13