EVALUATION OF RISK OF TRANSFUSION-TRANSMISSIBLE INFECTIONS IN BLOOD DONORS AT THE LAQUINTINIE HOSPITAL IN DOUALA, CAMEROON

Authors

  • Christiane Sike Medi Douala Laquintinie Hospital, Douala, Cameroon
  • Celestin Roger Ayangma Higher Institute of Medical Technology, Yaoundé, Cameroon
  • Esther Voundi
  • Annick Mintya Ndoumba Faculty of Medicine and Biomedical Sciences of The University of Yaoundé I, Yaoundé, Cameroon
  • Marie Paule Ngogang Faculty of Medicine and Biomedical Sciences of The University of Yaoundé I, Yaoundé, Cameroon
  • Bertrand Bille Eyoum Douala Laquintinie Hospital, Douala, Cameroon
  • Elisée Enyegue Embolo Ministry of Scientific Research and Innovation,Yaounde, Cameroon
  • Noël Emmanuel Essomba Faculty of Medicine and Pharmaceutical Sciences of The University of Douala, Douala, Cameroon

DOI:

https://doi.org/10.53555/nnmhs.v8i5.1289

Keywords:

transfusion, infection, blood donation, Cameroon.

Abstract

Unsafe blood transfusions have the potential to transmit a variety of infections known as transfusion-transmitted infections (TTIs). The overall objective of our study was to determine the seroprevalence and factors associated with TTIs related to human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), and Treponema pallidum bacteria among blood donors at the Laquintinie Hospital in Douala. Methodology: A cross-sectional analytical study was conducted among blood donors at the HDH for 12 months, from January 1 to December 30, 2021. HIV, HBV and HCV serological markers were tested by two immunological techniques, immuno-chromatography and Enzyme-Linked Immunosorbent Assays (ELISA). Treponema pallidum infection was tested by hemaglutination and ELISA. Factors associated with infection were investigated by multinomial logistic regression with a statistical significance level of 5%. Results: We analyzed 7222 blood bags, 1010 of which were positive for at least one of the infectious markers, i.e. a prevalence of TTI of 14.0%; this prevalence was significantly higher in male donors (p=0.001), those aged between 45 and 54 years (p=0.009), workers in the private sector (p=0.003), married donors (p=0.034). No significant difference was observed between compensatory and voluntary donation. Conclusion: TTIs remain a major public health concern, hence the need for awareness and surveillance strategies.

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Published

2022-07-08

Issue

Vol. 8 No. 5 (2022): Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425)

Section

Research Articles

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Copyright (c) 2022 Journal of Advance Research in Medical & Health Science

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How to Cite

Medi, C. S. ., Ayangma, C. R. ., Voundi, E. ., Ndoumba, A. M. ., Ngogang, M. P. ., Eyoum, B. B. ., Embolo, E. E. ., & Essomba, N. E. . (2022). EVALUATION OF RISK OF TRANSFUSION-TRANSMISSIBLE INFECTIONS IN BLOOD DONORS AT THE LAQUINTINIE HOSPITAL IN DOUALA, CAMEROON. Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425), 8(5), 20-27. https://doi.org/10.53555/nnmhs.v8i5.1289