ORAL HEALTH AND VITAMIN D IN ADULT: SYSTEMATIC REVIEW
DOI:
https://doi.org/10.53555/nnmhs.v9i1.1513Keywords:
Oral Health, Periodontitis, Steroid Hormone, Vitamin DAbstract
The role of nutrition in oral diseases has grown in popularity, and recent studies have revealed increasingly important links between nutritional deficiencies and oral pathologies. The levels of vitamin D (VD) have recently garnered an increasing amount of focus in the realm of oral health. VD deficit (VDD) is related with a wide array of oral health issues during growth and maturity; decreased VD synthesis may speed up the progression of some of these conditions. In children, severe VDD can produce faulty tooth mineralization, which can result in problems in both the dentin and the enamel. As a direct result of this, there is a potential for an increased risk of the beginning stages of dental caries as well as their advancement. In addition, VDD has been linked to a higher prevalence of periodontitis and gingival inflammation, and a number of recent research, both preclinical and clinical, have uncovered putative routes through which vitamin D may interact with the periodontium. The correction of VDD by supplementation may be one factor that contributes to the successful treatment of periodontitis; nevertheless, alveolar bone regeneration treatments conducted in individuals with baseline VDD appear to be more likely to fail. Some forms of oral cancer and osteonecrosis of the jaw may be connected to vitamin D, as may certain oral malignancies. This study seeks to present thorough evidence of how VD levels should be evaluated to maintain excellent oral health, as well as to describe how VDD may hinder oral development and its function in particular oral disorders.
References
Borel P, Caillaud D, Cano NJ. Vitamin D bioavailability: state of the art. Crit Rev Food Sci Nutr. 2015;55(9):1193–205.
Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr. April 2008;87(4):1080S-6S.
Turck D, Bresson JL, Burlingame B, Dean T, Fairweather-Tait S, Heinonen M. Update of the tolerable upper intake level for vitamin D for infants. EFSA Panel on Dietetic Products, Nutrition and Allergies (EFSA NDA Panel). Neuhauser-Berthold M. EFSA J. 16 (8): e05365. 2018.
Girgis CM, Clifton-Bligh RJ, Hamrick MW, Holick MF, Gunton JE. The roles of vitamin D in skeletal muscle: form, function, and metabolism. Endocr Rev. Februari 2013;34(1):33–83.
Kongsbak M, Levring TB, Geisler C, von Essen MR. The vitamin d receptor and T cell function. Front Immunol. 2013;4:148.
Morris HA, Anderson PH. Autocrine and paracrine actions of vitamin D. Clin Biochem Rev. 2010;31(4):129.
Watt RG, Daly B, Allison P, Macpherson LMD, Venturelli R, Listl S, et al. Ending the neglect of global oral health: time for radical action. Lancet (London, England). Juli 2019;394(10194):261–72.
Peres MA, Macpherson LMD, Weyant RJ, Daly B, Venturelli R, Mathur MR, et al. Oral diseases: a global public health challenge. Lancet (London, England). Juli 2019;394(10194):249–60.
Fathi N, Ahmadian E, Shahi S, Roshangar L, Khan H, Kouhsoltani M, et al. Role of vitamin D and vitamin D receptor (VDR) in oral cancer. Biomed Pharmacother. Januari 2019;109:391–401.
Ganesh ML, Pandian SK. Acceleration of tooth movement during orthodontic treatment-a frontier in orthodontics. J Pharm Sci Res. 2017;9(5):741.
Uwitonze AM, Murererehe J, Ineza MC, Harelimana EI, Nsabimana U, Uwambaye P, et al. Effects of vitamin D status on oral health. J Steroid Biochem Mol Biol. Januari 2018;175:190–4.
Anbarcioglu E, Kirtiloglu T, Öztürk A, Kolbakir F, Ac?kgöz G, Colak R. Vitamin D deficiency in patients with aggressive periodontitis. Oral Dis. Januari 2019;25(1):242–9.
Del Prete M, Mauriello MC, Faggiano A, Di Somma C, Monfrecola G, Fabbrocini G, et al. Insulin resistance and acne: a new risk factor for men? Endocrine. Desember 2012;42(3):555–60.
Antonoglou GN, Knuuttila M, Niemelä O, Ylöstalo P, Raunio T, Hiltunen L, et al. Serum parathyroid hormone and active vitamin D in chronic periodontitis. J Clin Periodontol. Agustus 2015;42(8):726–32.
Meghil MM, Hutchens L, Raed A, Multani NA, Rajendran M, Zhu H, et al. The influence of vitamin D supplementation on local and systemic inflammatory markers in periodontitis patients: A pilot study. Oral Dis. 2019;25(5):1403–13.
Patil VS, Mali RS, Moghe AS. Evaluation and comparison of Vitamin D receptors in periodontal ligament tissue of Vitamin D-deficient chronic periodontitis patients before and after supplementation of Vitamin D3. J Indian Soc Periodontol. 2019;23(2):100–5.
Gao W, Tang H, Wang D, Zhou X, Song Y, Wang Z. Effect of short-term vitamin D supplementation after nonsurgical periodontal treatment: A randomized, double-masked, placebo-controlled clinical trial. J Periodontal Res. Juni 2020;55(3):354–62.
McMahon L, Schwartz K, Yilmaz O, Brown E, Ryan LK, Diamond G. Vitamin D-mediated induction of innate immunity in gingival epithelial cells. Infect Immun. 2011;79(6):2250–6.
Chapple ILC, Bouchard P, Cagetti MG, Campus G, Carra M-C, Cocco F, et al. Interaction of lifestyle, behaviour or systemic diseases with dental caries and periodontal diseases: consensus report of group 2 of the joint EFP/ORCA workshop on the boundaries between caries and periodontal diseases. J Clin Periodontol. Maret 2017;44 Suppl 18:S39–51.
Darveau RP. Periodontitis: a polymicrobial disruption of host homeostasis. Nat Rev Microbiol. Juli 2010;8(7):481–90.
Dietrich T, Nunn M, Dawson-Hughes B, Bischoff-Ferrari HA. Association between serum concentrations of 25-hydroxyvitamin D and gingival inflammation–. Am J Clin Nutr. 2005;82(3):575–80.
Boggess KA, Espinola JA, Moss K, Beck J, Offenbacher S, Camargo Jr CA. Vitamin D status and periodontal disease among pregnant women. J Periodontol. 2011;82(2):195–200.
Wacker M, Holick MF. Vitamin D - effects on skeletal and extraskeletal health and the need for supplementation. Nutrients. Januari 2013;5(1):111–48.
Downloads
Published
Issue
Section
License
Copyright (c) 2023 Journal of Advance Research in Medical & Health Science
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Licensing
Ninety Nine Publication publishes articles under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This licensing allows for any use of the work, provided the original author(s) and source are credited, thereby facilitating the free exchange and use of research for the advancement of knowledge.
Detailed Licensing Terms
Attribution (BY): Users must give appropriate credit, provide a link to the license, and indicate if changes were made. Users may do so in any reasonable manner, but not in any way that suggests the licensor endorses them or their use.
No Additional Restrictions: Users may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
