NONALCOHOLIC FATTY LIVER DISEASE AND ALBUMINURIA : A SYSTEMATIC REVIEW
DOI:
https://doi.org/10.53555/gvhtv709Keywords:
Nonalcoholic fatty liver disease, Albuminuria, Incidence, CorrelationAbstract
Background: Non-alcoholic fatty liver disease (NAFLD) is associated with the dysregulation of multiple metabolic and inflammatory pathways. These can lead to extrahepatic disorders involving the kidney, a vulnerable organ responsible for extra-renal complications. Evaluating the association between NAFLD and low-grade albuminuria as a renal complication would be helpful to better understand the pathophysiology and extra-hepatic complications of NAFLD.The aim: This study aims to show incidence, correlation of nonalcoholic fatty liver disease and albuminuria Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. Result: Non-alcoholic fatty liver disease (NAFLD) is associated with the dysregulation of multiple metabolic and inflammatory pathways. These can lead to extrahepatic disorders involving the kidney, a vulnerable organ responsible for extra-renal complications. Evaluating the association between NAFLD and low-grade albuminuria as a renal complication would be helpful to better understand the pathophysiology and extra-hepatic complications of NAFLD.
Conclusion: Understanding the incidence, correlation of nonalcoholic fatty liver disease and allbuminuria
References
Wong VWS, Chan WK, Chitturi S, Chawla Y, Dan YY, Duseja A, et al. Asia–Pacific Working Party on Non-alcoholic Fatty Liver Disease guidelines 2017—Part 1: Definition, risk factors and assessment. Vol. 33, Journal of Gastroenterology and Hepatology (Australia). Blackwell Publishing; 2018. p. 70–85.
Chalasani N, Younossi Z, Lavine JE, Charlton M, Cusi K, Rinella M, et al. The Diagnosis and Management of Nonalcoholic Fatty Liver Disease: Practice Guidance From the American Association for the Study of Liver Diseases. 2017; Available from: http://journals.lww.com/hep
Ma B, Ju A, Zhang S, An Q, Xu S, Liu J, et al. Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease. Signal Transduct Target Ther. 2023 Dec 1;8(1).
Bernardi M, Angeli P, Claria J, Moreau R, Gines P, Jalan R, et al. Albumin in decompensated cirrhosis: new concepts and perspectives. Gut [Internet]. 2020 [cited 2023 Sep 13];69(6):1127–38. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282556/
Angulo P, Bugianesi E, Bjornsson ES, CHaratcharoenwitthaya P, Mills PR, Barrera F, et al. Simple Noninvasive Systems Predict Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease. Gastroenterology [Internet]. 2013 [cited 2023 Sep 13];145(4):782–9. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931256/
Sun L, Yin H, Liu M, Xu G, Zhou X, Ge P, et al. Impaired albumin function: a novel potential indicator for liver function damage? Vol. 51, Annals of Medicine. Taylor and Francis Ltd; 2019. p. 333–44.
Abbate M, Montemayor S, Mascaró CM, Casares M, Gómez C, Ugarriza L, et al. Albuminuria is associated with hepatic iron load in patients with non-alcoholic fatty liver disease and metabolic syndrome. J Clin Med. 2021 Jul 2;10(14).
Qin Z, Li H, Wang L, Geng J, Yang Q, Su B, et al. Systemic Immune-Inflammation Index Is Associated With Increased Urinary Albumin Excretion: A Population-Based Study. Front Immunol. 2022 Mar 21;13.
Kawaguchi K, Sakai Y, Terashima T, Shimode T, Seki A, Orita N, et al. Decline in serum albumin concentration is a predictor of serious events in nonalcoholic fatty liver disease. Medicine (Baltimore) [Internet]. 2021 [cited 2023 Sep 13];100(31). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341320/
Kang SH, Cho KH, Do JY. Non-alcoholic fatty liver disease is associated with low-grade albuminuria in men without diabetes mellitus. Int J Med Sci [Internet]. 2019 [cited 2023 Sep 13];16(2):285–91. Available from: https://www.medsci.org/v16p0285.htm
Sheng G, Peng N, Hu C, Zhong L, Zhong M, Zou Y. The albumin-to-alkaline phosphatase ratio as an independent predictor of future non-alcoholic fatty liver disease in a 5-year longitudinal cohort study of a non-obese Chinese population. Lipids Health Dis. 2021 Dec 1;20(1).
Younossi ZM, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M. Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology [Internet]. 2016 [cited 2023 Sep 13];64(1):73–84. Available from: https://pubmed.ncbi.nlm.nih.gov/26707365/
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