RISK FACTORS FOR PHYSICAL DISABILITY IN PATIENTS WITH LEPROSY: A SYSTEMATIC REVIEW
DOI:
https://doi.org/10.53555/bsz9y251Keywords:
Leprosy, Physical disability, Hansen diseaseAbstract
Background: Leprosy is also referred to as Hansen disease. It is a chronic granulomatous infection generally caused by Mycobacterium leprae and Mycobacterium lepromatosis, both of which primarily affects the skin and peripheral nerves. Physical disability (PD) can occur before leprosy diagnosis, during treatment and post-release from treatment. However, although patients may be exposed to risk factors that potentiate the risk of more severe PD they stop being routinely evaluated once the treatment of active leprosy has been completed.
The aim: This study aims to show about risk factor for physical disability in patients with leprosy.
Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.
Result: In the PubMed database, the results of our search brought up 104 articles, whereas the results of our search on SagePub brought up 77 articles. The results of the search conducted for the last year of 2013 yielded a total 88 articles for PubMed and 48 articles for SagePub. The result from title screening, a total 7 articles for PubMed and 28 articles for SagePub. In the end, we compiled a total of 10 papers. We included five research that met the criteria.
Conclusion: Delayed diagnosis, nerve damage, no skin lesions, WHO and Ridley-Jopling classifications, leprosy reactions, advanced age, rural occupation, Han ethnicity, and male sex were associated with disability in leprosy patients. Identifying risk factors could help to prevent physical disability.
References
. de Paula HL, de Souza CDF, Silva SR, Martins-Filho PRS, Barreto JG, Gurgel RQ, et al. Risk Factors for Physical Disability in Patients With Leprosy. JAMA Dermatology.
. Gilmore A, Roller J, Dyer JA. SCIENCE OF MEDICINE FEATURE SERIES Leprosy Hansen’s disease An Update and Review.
. Masresha BM, Yesuf KM, Moyehodie YA, Biresaw HB, Mulugeta SS, Addisia GD. Determinant factors of leprosy-related disability; comparison of acceleration failure time and parametric shared frailty models. PLoS One.
. Sanchez MN, Nery JS, Pescarini JM, Mendes AA, Ichihara MY, Teixeira CSS, et al. Physical disabilities caused by leprosy in 100 million cohort in Brazil. BMC Infect Dis.
. Reyila V, Betsy A, Riyaz N, Sasidharanpillai S, Beegum Sherjeena P, Majitha M, et al. Clinico-epidemiological study of disability due to leprosy at the time of diagnosis among patients attending a tertiary care institution. Indian J Dermatol.
. Mowla MR, Angkur DM, Hasan Z, Sultana MN, Afrin S, Akhter MS. Leprosy patients with deformities at post-elimination stage: The Bangladesh experience.
. Rathod SP, Jagati A, Chowdhary P. Disabilities in leprosy: an open, retrospective analyses of institutional records. An Bras Dermatol.
. Chowdhury S, Chakraborty P pratim. Universal health coverage There is more to it than meets the eye. J Fam Med Prim Care.
. Mulugeta SS, Maseresha BM, Wassihun SG, Moyehodie YA. Risk Factors for Disability Upgrading Among Leprosy Patients During Treatment: Multilevel Modeling Analysis. SAGE Open Nurs.
. Chen X, Liu HB, Shui TJ, Zha S. Risk factors for physical disability in patients with leprosy disease in yunnan, china: Evidence from a retrospective observational study. PLoS Negl Trop Dis.
. Dos Santos AR, Silva PRDS, Steinmann P, Ignotti E. Disability progression among leprosy patients released from treatment: A survival analysis. Infect Dis Poverty.
. Gunawan H, Kamilia A, Menaldi SL, Marissa M, Prakoeswa CRS, Alinda MD, et al. Characteristics of grade 2 disability in indonesian children with leprosy A five-year multicenter retrospective study. Clin Cosmet Investig Dermatol.
. Chen KH, Lin CY, Su S Bin, Chen KT. Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management. J Trop Med.
. Menaldi SL, Harini M, Nelfidayani N, Irawati Y, Setiono S, Wahyuni LK, et al. Functional activity limitation of leprosy cases in an endemic area in Indonesia and recommendations for integrated participation program in society. PLoS Negl Trop Dis
. Srinivas G, Muthuvel T, Lal V, Vaikundanathan K, Schwienhorst-Stich EM, Kasang C. Risk of disability among adult leprosy cases and determinants of delay in diagnosis in five states of India A case-control study. PLoS Negl Trop Dis.
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