WEIGHT LOSS FOR CHILDREN AND ADULTS WITH OBESITY AND ASTHMA: SYSTEMATIC REVIEW

Authors

  • Muhammad Pany A.A Faculty of Medicine, Muhammadiyah University of North Sumatera, Indonesia

DOI:

https://doi.org/10.53555/s2t5ry61

Keywords:

Asthma, adult asthma, children, obesity, weight loss

Abstract

Introduction: Asthma, a widespread respiratory condition affecting 339 million people globally, is closely associated with obesity, which is on the rise worldwide. This review examines the impact of weight loss on asthma in individuals dealing with obesity, drawing from randomized controlled trials in both children and adults.

Method: This study followed the 2020 PRISMA guidelines to ensure research alignment with necessary standards for accuracy. Articles were retrieved from databases including PubMed database in October 2023.  

Result: The search strategy produced a total of 14 results. Upon reviewing the titles and abstracts, we identified 8 papers that met the criteria for inclusion. Initially, 8 articles were excluded from consideration as they were written in a review format. After a thorough evaluation of the full-text papers, we ultimately included five papers in the final analysis, consisting of prospective analysis, cross-sectional study, retrospective analysis, experimental study, and secondary analysis to a randomized control trial.  

Conclusion: Diet significantly impacts respiratory health in non-overweight/non-obese children, while obesity is linked to severe asthma exacerbations, emphasizing the need for further research and public health campaigns. Short-term dietary interventions in obese asthmatic children successfully reduce calorie intake and sugar consumption, but improvements in other dietary aspects may take time, and physical activity plays a crucial role in weight loss, especially in those with lower baseline lung function. Adding exercise to weight loss interventions in obese adults with asthma yields multiple benefits, including reduced depression symptoms and improved asthma control, and moderate weight loss can delay dynamic hyperinflation, enhancing quality of life and clinical control, underscoring the significance of lifestyle interventions in managing asthma across different age groups.

References

. World Health Organization. Asthma fact sheet. 2017

. Peters U, Dixon AE, Forno E. Obesity and asthma. J Allergy Clin Immunol. 2018;141:1169–1179.

. Okoniewski W, Lu KD, Forno E. Weight Loss for Children and Adults with Obesity and Asthma. A Systematic Review of Randomized Controlled Trials. Ann Am Thorac Soc. 2019 May;16(5):613-625. doi: 10.1513/AnnalsATS.201810-651SR. PMID: 30605347; PMCID: PMC6491056.

. Silva, A. G., Freitas, P. D., Ferreira, P. G., Stelmach, R., Pinto, R. M. C., Salge, J. M., … Carvalho, C. R. F. (2018). Effects of weight loss on dynamic hyperinflation in women obese asthmatics. Journal of Applied Physiology. doi:10.1152/japplphysiol.00341.2018

. Rodrigues M, de Castro Mendes F, Padrão P, Delgado L, Paciência I, Barros R, Rufo JC, Silva D, Moreira A, Moreira P. Mediterranean Diet and Airway Inflammation in School-Aged Children. Children (Basel). 2023 Jul 29;10(8):1305. doi: 10.3390/children10081305. PMID: 37628304; PMCID: PMC10453938.

. Freitas PD, Ferreira PG, Silva AG, Stelmach R, Carvalho-Pinto RM, Fernandes FL, Mancini MC, Sato MN, Martins MA, Carvalho CR. The Role of Exercise in a Weight-Loss Program on Clinical Control in Obese Adults with Asthma. A Randomized Controlled Trial. Am J Respir Crit Care Med. 2017 Jan 1;195(1):32-42. doi: 10.1164/rccm.201603-0446OC. PMID: 27744739.

. Eslick S, Jensen ME, Collins CE, Gibson PG, Hilton J, Wood LG. Characterising a Weight Loss Intervention in Obese Asthmatic Children. Nutrients. 2020 Feb PMID: 32079331; PMCID: PMC7071161.

. Luthe SK, Hirayama A, Goto T, Faridi MK, Camargo CA Jr, Hasegawa K. Association Between Obesity and Acute Severity Among Patients Hospitalized for Asthma Exacerbation. J Allergy Clin Immunol Pract. 2018

. Watchorn D, Madden A, O'Shea D, Dunican EM, Butler MW. Weight Loss in Individuals with Obesity and Asthma. Ann Am Thorac Soc. 2019 30969796; PMCID: PMC6600830.

. Rebecca F. McLoughlin, Bronwyn S. Berthon, Lisa G. Wood, Weight loss in obese children with asthma – is it important Pa ediatric Respiratory Reviews, Volume 37, 2021,

Downloads

Published

2023-10-25

How to Cite

Pany A.A, M. . (2023). WEIGHT LOSS FOR CHILDREN AND ADULTS WITH OBESITY AND ASTHMA: SYSTEMATIC REVIEW. Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425), 9(10), 103-110. https://doi.org/10.53555/s2t5ry61