EVALUATION OF LONG TERM OUTCOMES ASSOCIATED WITH PRETERM EXPOSURE TO ANTENATAL CORTICOSTEROIDS : A SYSTEMATIC REVIEW

Authors

  • Rio Martin Rajagukguk PELNI General Hospital, Petamburan, Jakarta, Indonesia

DOI:

https://doi.org/10.53555/rb8c2e44

Keywords:

Preterm, antenatal, Corticosteroid

Abstract

The aim: This study aims to show about evaluation of long term outcomes associated with preterm exposure to antenatal corticosteroids.

Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up to date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.

Result: In the PubMed database, the results of our search brought up 117 articles, whereas the results of our search on SagePub brought up 112 articles. The results of the search conducted for the last year of 2013 yielded a total 91 articles for PubMed and 66 articles for SagePub. The result from title screening, a total 2 articles for PubMed and 11 articles for SagePub. In the end, we compiled a total of 8 papers. We included five research that met the criteria.

Conclusion: Numerous studies have shown no evidence of long-term harm (and in fact showed improved survival and neurodevelopmental outcomes with long-term pulmonary and others benefit), particulary as it relates to a single course of corticosteroids administered at less than 34 weeks of gestation.

References

. Amawat J, Wirayannawat W, Boonyanunt P, Paes B, Kitsommart R. Effects of antenatal dexamethasone on postnatal serum cortisol levels in late preterm infants. J Matern Neonatal Med [Internet]. 2023;36(2). Available from: https://doi.org/10.1080/14767058.2023.2224491

. Zhao J, Feng Z, Dai Y, Zhang W, Jiang S, Wang Y, et al. Use of antenatal corticosteroids among infants with gestational age at 24 to 31 weeks in 57 neonatal intensive care units of China: a cross-sectional study. Chin Med J (Engl). 2023;136(7):822–9.

. El-Sayed YY, Borders AEB, Gyamfi-Bannerman C. Antenatal Corticosteroid Therapy for Fetal Maturation. Vol. 130, Obstetrics and Gynecology. 2017. p. E102–9.

. Dagklis T, Sen C, Tsakiridis I, Villalaín C, Karel Allegaert, Wellmann S, et al. The use of antenatal corticosteroids for fetal maturation: Clinical practice guideline by the WAPM-World Association of Perinatal Medicine and the PMF-Perinatal Medicine foundation. J Perinat Med. 2022;50(4):375–85.

. Yao TC, Chang SM, Wu CS, Tsai YF, Sheen KH, Hong X, et al. Association between antenatal corticosteroids and risk of serious infection in children: nationwide cohort study. BMJ. 2023;382:e075835.

. Ushida T, Kotani T, Hayakawa M, Hirakawa A, Sadachi R, Nakamura N, et al. Antenatal corticosteroids and preterm offspring outcomes in hypertensive disorders of pregnancy: A Japanese cohort study. Sci Rep. 2020;10(1):1–10.

. Bae SP, Hahn WH, Park S, Jung YH, Park JY, Oh KJ, et al. Effects of antenatal corticosteroids on neonatal outcomes in twin and singleton pregnancies: A Korean national cohort study. BMJ Paediatr Open. 2023;7(1):1–9.

. Diguisto C, Arthuis C, Couderchet J, Morgan AS, Perrotin F, Rivière O, et al. Impact of antenatal corticosteroids on head circumference of full-term newborns: A French multicenter cohort study. Acta Obstet Gynecol Scand. 2020;99(9):1147–54.

. Räikkönen K, Gissler M, Tapiainen T, Kajantie E. Associations between Maternal Antenatal Corticosteroid Treatment and Psychological Developmental and Neurosensory Disorders in Children. JAMA Netw Open. 2022;5(8):E2228518.

. da Cunha AJLA, Rezende KB de C, Moreira MEL, da Gama SGN, Leal M do C. Use of antenatal corticosteroids in Brazil: Data analysis from the National Survey Nascer no Brasil. Rev Paul Pediatr. 2022;40.

. Yum SK, Lee JH. Dose completion of antenatal corticosteroids and neonatal outcomes in non-small-for-gestational age or small-for-gestational age very-low-birthweight infants: A Korean population-based cohort study. Pediatr Neonatol [Internet]. 2022;63(2):165–71. Available from: https://doi.org/10.1016/j.pedneo.2021.08.020

. Frier EM, Lin C, Reynolds RM, Allegaert K, Been J V., Fraser A, et al. Consortium for the Study of Pregnancy Treatments (Co-OPT): An international birth cohort to study the effects of antenatal corticosteroids. PLoS One. 2023;18(3 March):1–27.

. Reddy UM, Deshmukh U, Dude A, Harper L, Osmundson SS. Society for Maternal-Fetal Medicine Consult Series #58: Use of antenatal corticosteroids for individuals at risk for late preterm delivery: Replaces SMFM Statement #4, Implementation of the use of antenatal corticosteroids in the late preterm birth period in women at risk for preterm delivery, August 2016. Am J Obstet Gynecol [Internet]. 2021;225(5):B36–42. Available from: https://doi.org/10.1016/j.ajog.2021.07.023

. McDougall ARA, Aboud L, Lavin T, Cao J, Dore G, Ramson J, et al. Effect of antenatal corticosteroid administration-to-birth interval on maternal and newborn outcomes: a systematic review. eClinicalMedicine [Internet]. 2023;58:101916. Available from: https://doi.org/10.1016/j.eclinm.2023.101916

. Razaz N, Allen VM, Fahey J, Joseph KS. Antenatal Corticosteroid Prophylaxis at Late Preterm Gestation: Clinical Guidelines Versus Clinical Practice. J Obstet Gynaecol Canada [Internet]. 2023;45(5):319–26. Available from: https://doi.org/10.1016/j.jogc.2023.03.003

Downloads

Published

2023-11-06

How to Cite

Rajagukguk, R. M. . (2023). EVALUATION OF LONG TERM OUTCOMES ASSOCIATED WITH PRETERM EXPOSURE TO ANTENATAL CORTICOSTEROIDS : A SYSTEMATIC REVIEW. Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425), 9(11), 19-24. https://doi.org/10.53555/rb8c2e44