APPLICATION CARDIAC TROPONIN IN CARDIOVASCULAR DISEASES OTHER THAN ACUTE CORONARY SYNDROME: A SYSTEMATIC REVIEW

Authors

  • Anissa Paranoan General Practitioner, Stella Maris General Hospital, Makassar, Indonesia
  • Asriany Paranoan Faculty of Medicine, Hasanuddin University, Makassar, Indonesia

DOI:

https://doi.org/10.61841/yefwdw12

Keywords:

Cardiac troponin, cardiovascular disease, acute coronary syndrome.

Abstract

Background: Increased cardiac troponin concentrations in acute coronary syndrome (ACS) identify patients with ongoing cardiomyocyte necrosis who are at increased risk. However, with the use of more precise assays, cardiac troponin increases are commonly noted in other cardiovascular conditions as well.

The aim: This study aims to show application cardiac troponin in cardiovascular disease other than acute coronary syndrome.

Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.

Result: In the PubMed database, the results of our search brought up 211 articles, whereas the results of our search on SagePub brought up 221 articles. The results of the search conducted for the last year of 2013 yielded a total 65 articles for PubMed and 95 articles for SagePub. The result from title screening, a total 19 articles for PubMed and 30 articles for SagePub. In the end, we compiled a total of 10 papers. We included five research that met the criteria.

Conclusion: Increased cardiac troponin indicates increased risk for adverse outcome in patients with various cardiovascular conditions beyond ACS. Routine measurement of cardiac troponin concentrations can however, not be generally recommended unless there is a suspicion of ACS.

References

1. Sternberg M, Pasini E, Chen-Scarabelli C, Corsetti G, Patel H, Linardi D, et al. Elevated cardiac troponin in clinical scenarios beyond obstructive coronary artery disease. Med Sci Monit. 2019;25:7115–25.

2. Wang XY, Zhang F, Zhang C, Zheng LR, Yang J. The Biomarkers for Acute Myocardial Infarction and Heart Failure. Biomed Res Int. 2020;2020.

3. Chaulin A. Cardiac troponins: Contemporary biological data and new methods of determination. Vasc Health Risk Manag. 2021;17:299–316.

4. Chaulin AM. Cardiac Troponins as Biomarkers of Cardiac Myocytes Damage in Case of Arterial Hypertension: From Pathological Mechanisms to Predictive Significance. Life. 2022;12(9).

5. Tveit SH, Myhre PL, Hanssen TA, Forsdahl SH, Iqbal A, Omland T, et al. Cardiac troponin I and T for ruling out coronary artery disease in suspected chronic coronary syndrome. Sci Rep [Internet]. 2022;12(1):1–9. Available from: https://doi.org/10.1038/s41598-022-04850-7

6. Bularga A, Lee KK, Stewart S, Ferry A V., Chapman AR, Marshall L, et al. High-Sensitivity Troponin and the Application of Risk Stratification Thresholds in Patients with Suspected Acute Coronary Syndrome. Circulation. 2019;140(19):1557–68.

7. Kanani F, Maqsood S, Wadhwani V, Zubairy M, Iftikhar I, Zubairi AM. Diagnoses and Outcomes of Patients with Suspicion of Acute Coronary Syndrome and Raised High Sensitive Troponin I: A Single Center Study from Pakistan. J Lab Physicians. 2023;15(03):409–18.

8. Chapman AR, Adamson PD, Shah ASV, Anand A, Strachan FE, Ferry A V., et al. High-Sensitivity Cardiac Troponin and the Universal Definition of Myocardial Infarction. Circulation. 2020;141(3):161–71.

9. Oh AR, Lee SH, Park J, Choi DC, Yang K. Association between cardiac troponin testing at scheduled admission and mortality in patients with comorbidities. Ann Transl Med. 2023;11(1):7–7.

10. Kaier TE, Alaour B, Marber M. Cardiac troponin and defining myocardial infarction. Cardiovasc Res. 2021;117(10):2203–15.

11. Taggart C, Wereski R, Mills NL, Chapman AR. Diagnosis, investigation and management of patients with acute and chronic myocardial injury. J Clin Med. 2021;10(11).

12. Kim SJ, Mesquita FCP, Hochman-Mendez C. New Biomarkers for Cardiovascular Disease. Texas Hear Inst J. 2023;50(5):1–8.

13. Wright RS, Takhtehchian DS, Murphy JG. Cardiac Biomarkers. Mayo Clin Med Man. 2006;287–9.

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Published

2024-01-31

How to Cite

Paranoan, A. ., & Paranoan, A. . (2024). APPLICATION CARDIAC TROPONIN IN CARDIOVASCULAR DISEASES OTHER THAN ACUTE CORONARY SYNDROME: A SYSTEMATIC REVIEW. Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425), 10(1), 249-255. https://doi.org/10.61841/yefwdw12