ASSOCIATION OF OBESITY AND PSORIASIS: A TEN YEARS SYSTEMATIC REVIEW
DOI:
https://doi.org/10.61841/7tsw8956Keywords:
Psoriasis, obesityAbstract
Background: Psoriasis as a chronic inflammatory condition is often linked with metabolic disorders such as obesity, diabetes, dyslipidemia, and fatty liver disease. Research indicates a strong association between obesity and psoriasis, with obese individuals having a higher risk and severity of the condition. This study aims to systematically the association between psoriasis and obesity in literatures of the last 10 years.
Methods: This systematic review complied with the PRISMA 2020 standards and focused on full-text English literature published between 2014 and 2024. Articles such as editorials and review papers from the same journal, as well as submissions lacking a DOI, were excluded from consideration. Literature was sourced from online platforms like PubMed and SagePub.
Result: We found 698 articles on PubMed and 1157 articles on SagePub. Restricting our search to the past decade (2014-2024), PubMed presented 606 articles, whereas SagePub presented 633 articles. From these, we selected 5 papers meeting our criteria, with 2 from PubMed and 3 from SagePub.
Conclusion: Psoriasis is a chronic inflammatory skin disease caused by a complex interplay between immune and host cells. Obesity and nutrition play pivotal roles in its onset and severity through adipocytokin levels. Inflammation in psoriasis increases free radical production, necessitating antioxidants to maintain redox balance, suggesting that diets rich in antioxidants may help alleviate symptoms.
References
Jensen P, Skov L. Psoriasis and Obesity. Dermatology. 2016;232(6):633–9.
Kunz M, Simon JC, Saalbach A. Psoriasis: Obesity and Fatty Acids. Front Immunol. 2019;10:1807.
Gisondi P, Del Giglio M, Girolomoni G. Considerations for Systemic Treatment of Psoriasis in Obese Patients. Am J Clin Dermatol. 2016 Dec;17(6):609–15.
Norden A, Rekhtman S, Strunk A, Garg A. Risk of psoriasis according to body mass index: A retrospective cohort analysis. Journal of the American Academy of Dermatology [Internet]. 2022 May 1 [cited 2024 Feb 15];86(5):1020–6. Available from: https://www.sciencedirect.com/science/article/pii/S0190962221011129
Cohen SB, Gern BH, Delahaye JL, Adams KN, Plumlee CR, Winkler JK, et al. Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination. Cell Host Microbe. 2018 Sep 12;24(3):439-446.e4.
Ando Y, Iimura J, Arai S, Arai C, Komori M, Tsuyumu M, et al. Risk factors for recurrent epistaxis: Importance of initial treatment. Auris Nasus Larynx [Internet]. 2014 Feb 1 [cited 2024 Feb 15];41(1):41–5. Available from: https://www.sciencedirect.com/science/article/pii/S0385814613001429
Abrich V, Brozek A, Boyle TR, Chyou PH, Yale SH. Risk Factors for Recurrent Spontaneous Epistaxis. Mayo Clinic Proceedings [Internet]. 2014 Dec 1 [cited 2024 Feb 15];89(12):1636–43. Available from: https://www.sciencedirect.com/science/article/pii/S0025619614008349
Lou ZC, Jin KF. Randomized Comparative Study of Microwave Ablation and Electrocautery for Control of Recurrent Epistaxis. Ear Nose Throat J [Internet]. 2021 Aug 1 [cited 2024 Feb 15];100(7):509–15. Available from: https://doi.org/10.1177/0145561319879238
McWilliams JP, Majumdar S, Kim GH, Lee J, Seals K, Tangchaiburana S, et al. North American Study for the Treatment of Recurrent Epistaxis with Doxycycline: The NOSTRIL trial. Journal of Thrombosis and Haemostasis [Internet]. 2022 May 1 [cited 2024 Feb 15];20(5):1115–25. Available from: https://www.sciencedirect.com/science/article/pii/S1538783622001568
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Licensing
Ninety Nine Publication publishes articles under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This licensing allows for any use of the work, provided the original author(s) and source are credited, thereby facilitating the free exchange and use of research for the advancement of knowledge.
Detailed Licensing Terms
Attribution (BY): Users must give appropriate credit, provide a link to the license, and indicate if changes were made. Users may do so in any reasonable manner, but not in any way that suggests the licensor endorses them or their use.
No Additional Restrictions: Users may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
