PROBIOTICS FOR PREVENTION OF NECROTIZING ENTEROCOLITIS : A COMPREHENSIVE SYSTEMATIC REVIEW
DOI:
https://doi.org/10.61841/at14a173Keywords:
Probiotics, necrotizing enterocolitis, infantsAbstract
Background: Necrotizing enterocolitis (NEC) is the most common serious acquired disease of the gastrointestinal tract in preterm infants. It is characterized by bowel wall necrosis, of various length and depth. Bowel perforation occurs in one third of the affected infants. Although 5 to 25 of cases occur in term infants, it is primarily a disease of preterm infants with the majority of cases occurring in very low birth weight infants (infants with birth weight 1500 g).
The aim: This study aims to show about probiotics for prevention of nercrotizing enterocolitis.
Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.
Result: In the PubMed database, the results of our search brought up 26 articles, whereas the results of our search on SagePub brought up 48 articles, on Google Scholar 5660 articles. The results of the search conducted for the last year of 2014 yielded a total 15 articles for PubMed, 35 articles for SagePub, and 4567 articles for Google Scholar. The result from title screening, a total 11 articles for PubMed, 16 articles for SagePub, and 8 for Google Scholar. In the end, we compiled a total of 10 papers. We included five research that met the criteria.
Conclusion: The risk-benefit ratio depends on the incidence of NEC in a neonatal intensive care unit, and evidence has shown that preventive measures probiotic administration can result in a decrease in NEC.
References
Hussain M, Jabeen S, Subhani RUH. Role of probiotics in prevention of nectrotizing enterocolitis in preterm low birth weight neonates. Pakistan J Med Heal Sci. 2016;10(2):455–9.
Alfaleh K, Anabrees J. Probiotics for prevention of necrotizing enterocolitis in preterm infants. Cochrane Database Syst Rev. 2014;2014(4).
Robinson JL. Probiotics for prevention of necrotizing enterocolitis—where do we stand in 2017? J Lab Precis Med. 2017;2:19–19.
Seghesio E, De Geyter C, Vandenplas Y. Probiotics in the prevention and management of necrotizing enterocolitis. Probiotics Prev Manag Hum Dis A Sci Perspect. 2022;24(3):93–9.
Beghetti I, Panizza D, Lenzi J, Gori D, Martini S, Corvaglia L, et al. Probiotics for preventing necrotizing enterocolitis in preterm infants: A network meta-analysis. Nutrients. 2021;13(1):1–14.
Meyer MP, Chow SSW, Alsweiler J, Bourchier D, Broadbent R, Knight D, et al. Probiotics for Prevention of Severe Necrotizing Enterocolitis: Experience of New Zealand Neonatal Intensive Care Units. Front Pediatr. 2020;8(April):1–9.
Denkel LA, Schwab F, Garten L, Geffers C, Gastmeier P, Piening B. Protective effect of dual-strain probiotics in preterm infants: A multi-center time series analysis. PLoS One. 2016;11(6):1–20.
Chowdhury T, Ali MM, Hossain MM, Singh J, Yousuf ANM, Yasmin F, et al. Efficacy of probiotics versus placebo in the prevention of necrotizing enterocolitis in preterm very low birth weight infants: A double-blind randomized controlled trial. J Coll Physicians Surg Pakistan. 2016;26(9):770–4.
Arora S, Khurana MS, Saini R. To study the role of probiotics in the prevention of necrotizing enterocolitis in preterm neonates. Int J Contemp Pediatr. 2017;4(5):1792.
Amini E, Dalili H, Niknafs N, Shariat M, Nakhostin M, Jedari-Attari S. The effect of probiotics in prevention of necrotising enterocolitis in preterm neonates in comparison with control group. Iran J Pediatr. 2017;27(6).
Zhang Y, Xu Q, Zhang F, Sun C. Probiotics for Preventing Necrotizing Enterocolitis: A Meta-Analysis with Trial Sequential Analysis. J Clin Pharm Ther. 2023;2023.
Rees CM, Hall NJ, Fleming P, Eaton S. Probiotics for the prevention of surgical necrotising enterocolitis: Systematic review and meta-analysis. BMJ Paediatr Open. 2017;1(1):1–8.
Aceti A, Gori D, Barone G, Callegari ML, Di Mauro A, Fantini MP, et al. Probiotics for prevention of necrotizing enterocolitis in preterm infants: systematic review and meta-analysis. Ital J Pediatr [Internet]. 2015;41(1). Available from: http://dx.doi.org/10.1186/s13052-015-0199-2
Murphy K, Ross RP, Ryan CA, Dempsey EM, Stanton C. Probiotics, Prebiotics, and Synbiotics for the Prevention of Necrotizing Enterocolitis. Front Nutr. 2021;8(September):1–10.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Licensing
Ninety Nine Publication publishes articles under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This licensing allows for any use of the work, provided the original author(s) and source are credited, thereby facilitating the free exchange and use of research for the advancement of knowledge.
Detailed Licensing Terms
Attribution (BY): Users must give appropriate credit, provide a link to the license, and indicate if changes were made. Users may do so in any reasonable manner, but not in any way that suggests the licensor endorses them or their use.
No Additional Restrictions: Users may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
