DIAGNOSIS AND TREATMENT OF STATUS EPILEPTICUS : AN UPDATE SYSTEMATIC REVIEW
DOI:
https://doi.org/10.61841/gdrmpz79Keywords:
Status epilepticus, refractory epilepticus, seizure, diagnosis, management.Abstract
Background: Status epilepticus (SE) is a condition resulting from the failure of the mechanisms involved in termination or the initiation of mechanisms responsible for seizure prolongation.
The aim: The aim of this study to show about diagnosis and treatment of status epilepticus.
Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Google Scholar were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.
Result: In the PubMed database, the results of our search get 110 articles, whereas the results of our search on SagePub get 163 articles, on Google Scholar 8200 articles. Records remove before screening are 7182, so we get 2761 articles fos screening. After we screened based on record exclude, we compiled a total of 10 papers. We included five research that met the criteria.
Conclusion: There are increasingly more drug options to treat SE, but rational polytherapy should consider the pharmacodynamics and kinetics of established and new antiepileptic drugs. When seizures cannot be controlled with conventional medical therapy, non-conventional treatments, including early surgical evaluation can be considered; however, high-quality evidence for these strategies are lacking. Neurointensivists are challenged to reduce secondary brain injury by managing common complications.
References
Pinto LF, de Oliveira JPS, Midon AM. Status epilepticus: review on diagnosis, monitoring and treatment. Arq Neuropsiquiatr. 2022;80(5):193–203.
Akamatsu N, Tsuji S. Current diagnosis and treatment of status epilepticus. Clin Neurol. 2003;43(11):799–801.
Poblete R, Sung G. Status Epilepticus and Beyond: A Clinical Review of Status Epilepticus and an Update on Current Management Strategies in Super-refractory Status Epilepticus. Korean J Crit Care Med. 2017;32(2):89–105.
Al-Sofyani KA. An Insight into the Current Understanding of Status Epilepticus: From Concept to Management. Neurol Res Int. 2021;2021.
Byun JI. Management of convulsive status epilepticus: recent updates. Encephalitis. 2023;3(2):39–43.
Rollo E, Romozzi M, Dono F, Bernardo D, Consoli S, Anzellotti F, et al. Treatment of benzodiazepine-refractory status epilepticus: A retrospective, cohort study. Epilepsy Behav [Internet]. 2023;140:109093. Available from: https://doi.org/10.1016/j.yebeh.2023.109093
Chiarello D, Duranti F, Lividini A, Maltoni L, Spadoni C, Taormina S, et al. Clinical characterization of status epilepticus in childhood: a retrospective study in 124 patients. Seizure [Internet]. 2020;78(February):127–33. Available from: https://doi.org/10.1016/j.seizure.2020.03.019
Sairanen JJ, Kantanen AM, Hyppölä HT, Kälviäinen RK. Treatment delay in status epilepticus - More effective prehospital symptom recognition warranted. Scand J Trauma Resusc Emerg Med. 2019;27(1):4–10.
Hidalgo de la Cruz M, Miranda Acuña JA, Luque Buzo E, Chavarria Cano B, Esteban de Antonio E, Prieto Montalvo J, et al. Manejo y factores de riesgo de mortalidad del estatus epiléptico: estudio retrospectivo. Neurología. 2022;37(7):532–42.
Abbasi H, Leach JP. Retrospective Study of Status Epilepticus in Adults in Glasgow From 1996–2013. J Neurol Neurosurg Psychiatry. 2016;87(12):e1.1-e1.
Glauser T, Shinnar S, Gloss D, Alldredge B, Arya R, Bainbridge J, et al. Evidence-based guideline: Treatment of convulsive status epilepticus in children and adults: Report of the guideline committee of the American epilepsy society. Epilepsy Curr. 2016;16(1):48–61.
Singh SP, Agarwal S, Faulkner M. Refractory status epilepticus. Ann Indian Acad Neurol. 2014;17(SUPPL. 1).
Müller A, Schmiedeknecht A, Mende M, Awissus C, Rosenow F, Hamer H, et al. Treatment of established status epilepticus in the elderly - a study protocol for a prospective multicenter double-blind comparative effectiveness trial (ToSEE). BMC Neurol. 2020;20(1):1–9.
Khoueiry M, Alvarez V. Status epilepticus in adults: a clinically oriented review of etiologies, diagnostic challenges, and therapeutic advances. Clin Epileptol. 2023;36(4):288–97.
Crawshaw AA, Cock HR. Medical management of status epilepticus: Emergency room to intensive care unit. Seizure [Internet]. 2020;75(March 2019):145–52. Available from: https://doi.org/10.1016/j.seizure.2019.10.006
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