PREVALENCE, SURGICAL MANAGEMENT, AND OUTCOME OF PERFORATION OF THE GASTER ASSOCIATED WITH LONG TERM CORTICOSTEROID USE : A COMPREHENSIVE SYSTEMATIC REVIEW
DOI:
https://doi.org/10.61841/4rpqfb44Keywords:
Gaster, perforation, corticosteroid, surgical, outcomeAbstract
Background: In the general population, gastroduodenal perforation can occur as a complication of pre-existing peptic ulcer disease (PUD). In this scenario, the morbidity and mortality are already well documented. The lifetime risk of perforation is approximately 2–10 in cases of untreated PUD, and despite an improvement in resuscitation, and intensive and surgical care, the mortality rate remains around 25.
The aim: The aim of this study to show about prevalence, surgical management, and outcome of perforation of the gaster associated with long term corticosteroid use.
Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Google Scholar were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.
Result: In the PubMed database, the results of our search get 28 articles, whereas the results of our search on SagePub get 9 articles, on Google Scholar 1680 articles. Records remove before screening are 759, so we get 958 articles fos screening. After we screened based on record exclude, we compiled a total of 10 papers. We included five research that met the criteria.
Conclusion: The location of ulcers within the stomach affects the surgical procedure. They may appear with a smaller sac abscess, commonly linked with peritonitis or retroperitoneal abscess. Gastric perforation is a serious and fatal disorder, especially in those who are underweight. Early diagnosis, basic care, primary management, stabilization, nutrient diet, and surgical exploration are all part of initial management.
References
Chilkoti G, Singh A, Mohta M, Saxena A. Perioperative “stress dose” of corticosteroid: Pharmacological and clinical perspective. J Anaesthesiol Clin Pharmacol [Internet]. 2019;35(2):147. Available from: https://journals.lww.com/10.4103/joacp.JOACP_242_17
He JN, Tian Z, Yao X, Li HY, Yu Y, Liu Y, et al. Multiple perforations and fistula formation following corticosteroid administration: A case report. World J Clin Cases. 2017;5(2):67.
Narum S, Westergren T, Klemp M. Corticosteroids and risk of gastrointestinal bleeding: A systematic review and meta-analysis. BMJ Open. 2014;4(5):1–9.
Hox V, Lourijsen E, Jordens A, Aasbjerg K, Agache I, Alobid I, et al. Benefits and harm of systemic steroids for short- And long-term use in rhinitis and rhinosinusitis: An EAACI position paper. Clin Transl Allergy [Internet]. 2020;10(1):1–27. Available from: https://doi.org/10.1186/s13601-019-0303-6
Mazepa MM, Pereira MA, Arabi AYM, Dias AR, Ribeiro U, Zilberstein B, et al. Gastroduodenal Perforation in Cancer Patients: Association with Chemotherapy and Prognosis. Med Sci. 2023;11(2):26.
Dalal AA, Duh MS, Gozalo L, Robitaille MN, Albers F, Yancey S, et al. Dose-response relationship between long-term systemic corticosteroid use and related complications in patients with severe asthma. J Manag Care Spec Pharm. 2016;22(7):833–47.
Zhang L, Huang H, Wang Z, Fang X, Hong H, Chen Y, et al. A study on the prevention of hemorrhage and perforation in patients with primary gastric diffuse large-B cell lymphoma during treatment with immunochemotherapy. Cancer Med. 2023;12(6):6924–34.
Dadfar A, Edna TH. Epidemiology of perforating peptic ulcer: A population-based retrospective study over 40 years. World J Gastroenterol. 2020;26(35):5302–13.
Broersen LHA, Horváth-Puhó E, Pereira AM, Erichsen R, Dekkers OM, Sørensen HT. Corticosteroid use and mortality risk in patients with perforated colonic diverticular disease: A population-based cohort study. BMJ Open Gastroenterol. 2017;4(1):1–8.
Alder AC, Minkes RK. Gastric Perforation. Pediatr Surg Gen Princ Newborn Surg Vol 1. 2020;1:865–73.
Yasir M, Sonthalia S. Corticosteroid Adverse Effects. StatPearls [Internet]. 2019;1–12. Available from: http://www.ncbi.nlm.nih.gov/pubmed/30285357
Nguyen MHK, Isaac KM, Dougherty R. Gastrointestinal perforation: relation to corticosteroid use and COPD – a case report. J Community Hosp Intern Med Perspect. 2016;6(4):32129.
Wada M, Onda M, Tokunaga A, Kiyama T, Yoshiyuki T, Matsukura N, et al. Spontaneous gastrointestinal perforation in patients with lymphoma receiving chemotherapy and steroids. Report of three cases. Vol. 66, Journal of Nippon Medical School. 1999. p. 37–40.
Caplan A, Fett N, Rosenbach M, Werth VP, Micheletti RG. Prevention and management of glucocorticoid-induced side effects: A comprehensive review: Gastrointestinal and endocrinologic side effects. J Am Acad Dermatol [Internet]. 2017;76(1):11–6. Available from: http://dx.doi.org/10.1016/j.jaad.2016.02.1239
Mishra BN, Kumar D, Mishra G. A Case of Steroid-Induced Gastric Perforation in a Ten-Year-Old Child. Cureus. 2024;16(1):7–9.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Yosefina Raju Marito, Yohanes Deni Brianto
This work is licensed under a Creative Commons Attribution 4.0 International License.
Licensing
Ninety Nine Publication publishes articles under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This licensing allows for any use of the work, provided the original author(s) and source are credited, thereby facilitating the free exchange and use of research for the advancement of knowledge.
Detailed Licensing Terms
Attribution (BY): Users must give appropriate credit, provide a link to the license, and indicate if changes were made. Users may do so in any reasonable manner, but not in any way that suggests the licensor endorses them or their use.
No Additional Restrictions: Users may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
