SEROPREVALENCE OF THE HUMAN IMMUNODEFICIENCY VIRUS AND IMPACT ON FERTILITY IN COUPLES AT THE GYNAECOLOGICAL ENDOSCOPIC SURGERY AND HUMAN REPRODUCTIVE TEACHING HOSPITAL, CAMEROON

Authors

  • Junior Voundi Voundi Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon
  • Etienne Belinga Gynaecological Endoscopic Surgery and Human Reproductive Teaching Hospital, Cameroon
  • Esther Voundi Voundi Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon
  • Claude Noa Ndoua Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon
  • Serge Nyada Gynaecological Endoscopic Surgery and Human Reproductive Teaching Hospital, Cameroon
  • Vanina Ngono Gynaecological Endoscopic Surgery and Human Reproductive Teaching Hospital, Cameroon
  • Simon Stevensen Sahmo Gynaecological Endoscopic Surgery and Human Reproductive Teaching Hospital, Cameroon
  • Louise Nyimbe Mviena Gynaecological Endoscopic Surgery and Human Reproductive Teaching Hospital, Cameroon
  • Nguefack Tsague Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon
  • Michel Toukam Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon

DOI:

https://doi.org/10.53555/nnpbs.v8i4.1207

Keywords:

HIV, infertility, tubo-ovarian union, oligospermia, GESHRTH, Cameroon

Abstract

Introduction: HIV biology may explain subfertility in infected patients. The objective of our study was to evaluate the impact of HIV infection on the male and female fertility of couples followed at the Gynaecological Endoscopic Surgery and Human Reproductive Teaching Hospital (GESHRTH).

Methodology: an analytical cross-sectional study was conducted over a period of 9 months from January 1st to September 1st, 2019 at the GESHRTH. A total of 279 complete files were included in our study consecutively. The qualitative variables were compared using a Chi² test or Fisher’s exact test using Epi Info software version 3.5.4 with a statistically significant threshold, p<5%.

Results: The most represented female morphological abnormalities were tubo-ovarian adhesions, i.e. 48.4% (135), followed by uterine fibroids, i.e. 32.2% (90). Concerning men, 50.9% (142) had spermogram abnormalities among which oligospermia (42.7%) was mainly found. HIV seroprevalence was higher in women (36; 12.9%) than in men (12; 4.3%). The type of infertility and the morphological etiologies of female infertility were not related to HIV infection. On the other hand, all HIV-positive men (100%) had a sperm abnormality which was oligospermia (p < 0.001).

Conclusion: HIV could have an impact on the occurrence of sperm abnormalities including oligospermia. However, prospective studies should be conducted to further investigate the impact of HIV on fertility.

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Published

2022-04-13

How to Cite

Voundi, J. V. ., Belinga, E. ., Voundi, E. V. ., Ndoua, C. N. ., Nyada, S. ., Ngono, V. ., Sahmo, S. S. ., Mviena, L. N. ., Tsague, N. ., & Toukam, M. . (2022). SEROPREVALENCE OF THE HUMAN IMMUNODEFICIENCY VIRUS AND IMPACT ON FERTILITY IN COUPLES AT THE GYNAECOLOGICAL ENDOSCOPIC SURGERY AND HUMAN REPRODUCTIVE TEACHING HOSPITAL, CAMEROON. Journal of Advance Research in Pharmacy &Amp; Biological Science, 8(4), 9–14. https://doi.org/10.53555/nnpbs.v8i4.1207

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