SEROPREVALENCE OF THE HUMAN IMMUNODEFICIENCY VIRUS AND IMPACT ON FERTILITY IN COUPLES AT THE GYNAECOLOGICAL ENDOSCOPIC SURGERY AND HUMAN REPRODUCTIVE TEACHING HOSPITAL, CAMEROON
Keywords:HIV, infertility, tubo-ovarian union, oligospermia, GESHRTH, Cameroon
Introduction: HIV biology may explain subfertility in infected patients. The objective of our study was to evaluate the impact of HIV infection on the male and female fertility of couples followed at the Gynaecological Endoscopic Surgery and Human Reproductive Teaching Hospital (GESHRTH).
Methodology: an analytical cross-sectional study was conducted over a period of 9 months from January 1st to September 1st, 2019 at the GESHRTH. A total of 279 complete files were included in our study consecutively. The qualitative variables were compared using a Chi² test or Fisher’s exact test using Epi Info software version 3.5.4 with a statistically significant threshold, p<5%.
Results: The most represented female morphological abnormalities were tubo-ovarian adhesions, i.e. 48.4% (135), followed by uterine fibroids, i.e. 32.2% (90). Concerning men, 50.9% (142) had spermogram abnormalities among which oligospermia (42.7%) was mainly found. HIV seroprevalence was higher in women (36; 12.9%) than in men (12; 4.3%). The type of infertility and the morphological etiologies of female infertility were not related to HIV infection. On the other hand, all HIV-positive men (100%) had a sperm abnormality which was oligospermia (p < 0.001).
Conclusion: HIV could have an impact on the occurrence of sperm abnormalities including oligospermia. However, prospective studies should be conducted to further investigate the impact of HIV on fertility.
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