Application of Dynamic Magnetic Fields to B16-BL6 Melanoma Cells Linked with Decrease in Cellular Viability After Short Exposures
DOI:
https://doi.org/10.53555/nnpbs.v1i6.566Keywords:
rotating magnetic fields, electromagnetic fields, B16-BL6 melanoma, vibration, interleukinsAbstract
This experiment was designed to test the effects of an extremely low frequency electromagnetic field (ELF-EMF) generator (‘Resonator’) compared with strong static magnetic fields on cellular viability, and to illustrate the importance of dynamic patterns of fields compared with static patterns.
References
Adey, W. R. (1981). "Tissue interactions with nonionizing electromagnetic fields." Physiological reviews 61(2):435
Adey, W. R. (1993). "Biological effects of electromagnetic fields." Journal of cellular biochemistry 51: 410-410
Aggarwal, B. B. (2003). "Signalling pathways of the TNF superfamily: a double-edged sword." Nature Reviews Immunology 3(9): 745-756
Barnothy, M. F. (1964). Biological effects of magnetic fields, Plenum Press New York
Blank, M. and R. Goodman (1997). "Do electromagnetic fields interact directly with DNA?" Bioelectromagnetics 18(2): 111-115
Blank, M. and R. Goodman (1999). "Electromagnetic fields may act directly on DNA." Journal of cellular biochemistry 75(3): 369-374
Buckner, C. A. (2011). Effects of electromagnetic fields on biological processes are spatial and temporaldependent. PhD, Laurentian University
Curry, B. D., J. L. Bain, J. G. Yan, L. L. Zhang, M. Yamaguchi, H. S. Matloub and D. A. Riley (2002). "Vibration injury damages arterial endothelial cells." Muscle & nerve 25(4): 527-534
Goodman, R. and M. Blank (1998). "Magnetic field stress induces expression of hsp70." Cell stress & chaperones 3(2): 79
Goodman, R. and M. Blank (2002). "Insights into electromagnetic interaction mechanisms." Journal of cellular physiology 192(1): 16-22
Goodman, R., M. Blank, H. Lin, R. Dai, O. Khorkova, L. Soo, D. Weisbrot and A. Henderson (1994). "Increased levels of hsp70 transcripts induced when cells are exposed to low frequency electromagnetic fields." Bioelectrochemistry and bioenergetics 33(2): 115-120
Hu, J. H., L. S. St-Pierre, C. A. Buckner, R. M. Lafrenie and M. A. Persinger (2010). "Growth of injected melanoma cells is suppressed by whole body exposure to specific spatial-temporal configurations of weak intensity magnetic fields." International journal of radiation biology 86(2): 79-88
Kiray, A., H. Tayefi, M. Kiray, H. A. Bagriyanik, C. Pekcetin, B. U. Ergur and C. Ozogul (2013). "The effects of exposure to electromagnetic field on rat myocardium." Toxicology and Industrial Health 29(5): 418-425
Kwee, S., P. Raskmark and S. Velizarov (2001). "Changes in cellular proteins due to environmental non-ionizing radiation. I. Heat-shock proteins." Electromagnetic Biology and Medicine 20(2): 141-152
Lang, P. G. (2002). "Current concepts in the management of patients with melanoma." American journal of clinical dermatology 3(6): 401-426
Levin, M. (2013). "Reprogramming cells and tissue patterning via bioelectrical pathways: molecular mechanisms and biomedical opportunities." Wiley Interdisciplinary Reviews: Systems Biology and Medicine 5(6): 657-676
Lim, H. B., G. G. Cook, A. T. Barker and L. A. Coulton (2005). "Effect of 900 MHz electromagnetic fields on nonthermal induction of heat-shock proteins in human leukocytes." Radiation research 163(1): 45-52
Lin, H., M. Opler, M. Head, M. Blank and R. Goodman (1997). "Electromagnetic field exposure induces rapid, transitory heat shock factor activation in human cells." Journal of cellular biochemistry 66(4): 482-488
Martin, L., S. Koren and M. Persinger (2004). "Thermal analgesic effects from weak, complex magnetic fields and pharmacological interactions." Pharmacology Biochemistry and Behavior 78(2): 217-227
Murugan, N. J., L. M. Karbowski, R. M. Lafrenie and M. A. Persinger (2013). "Temporally-Patterned Magnetic Fields Induce Complete Fragmentation in Planaria." PloS one 8(4): e61714
Nelson, B. H. (2004). "IL-2, regulatory T cells, and tolerance." The Journal of Immunology 172(7): 3983-3988. Nowak, A., M. Pawlak, M. Brychcy, J. Celichowski and P. Krutki (2012). "Effects of brief whole-body vibration on bone metabolic and immunological indices in rats."
Persinger, M. (2010). "10-20 Joules as a Neuromolecular Quantum in Medicinal Chemistry: An Alternative Approach to Myriad Molecular Pathways?" Current Medicinal Chemistry 17(27): 3094-3098
Persinger, M. A. (2014). "Infrasound, human health, and adaptation: an integrative overview of recondite hazards in a complex environment." Natural Hazards 70(1): 501-525
Pilla, A. A. (2003). "Weak time-varying and static magnetic fields: from mechanisms to therapeutic applications." Biological Effects of Electromagnetic Fields, Stavroulakis P, ed., Springer Verlag: 34-75
Puig, F., F. Rico, I. Almendros, J. M. Montserrat, D. Navajas and R. Farre (2005). "Vibration enhances interleukin-8 release in a cell model of snoring induced airway inflammation." SLEEP-NEW YORK THEN WESTCHESTER- 28(10): 1312
Raylman, R. R., A. C. Clavo and R. L. Wahl (1996). "Exposure to strong static magnetic field slows the growth of human cancer cells in vitro."
Russo, A., A. Banes, M. Elfervig and M. Tsuzaki (2002). The effect of vibration on annulus cell signaling. Proceedings of the NASS 16th Annual Meeting/The Spine Journal, Elsevier
Santini, M. T., G. Rainaldi and P. L. Indovina (2009). "Cellular effects of extremely low frequency (ELF) electromagnetic fields." International Journal of Radiation Biology 85(4): 294-313
Shahidain, R. M., JE Sisken, R (2001). "Calcium spiking activity and baseline calcium levels in ROS 17/2.8 cells exposed to extremely low frequency electromagnetic fields (ELF EMF)." International journal of radiation biology 77(2): 241-248
Söker, S., C. Sert, M. Deniz, I. Tekmen, M. Akkus, Y. Nergiz, S. SÖKER, C. SERT, M. DENIZ and I. TEKMEN (2011). "The Effects of Electromagnetic Fields on the Ultrastructure of Heart." Int. J. Morphol 29(3): 960-964
Stavroulakis, P. (2003). Biological effects of electromagnetic fields: Mechanisms, modeling, biological effects, therapeutic effects, international standards, exposure criteria, Springer
Tayefi, H., A. Kiray, M. Kiray, B. U. Ergur, H. A. Bagriyanik, C. Pekcetin, M. Fidan and C. Ozogul (2010). "The effects of prenatal and neonatal exposure to electromagnetic fields on infant rat myocardium." Arch Med Sci 6(6): 837-842
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